The Effects of Taurine on Excitable Tissues

Proceedings of the 21st Annual A. N. Richards Symposium of the Physiological Society of Philadelphia, Valley Forge, Pennsylvania, April 23–24, 1979

  • S. W. Schaffer
  • Steven I. Baskin
  • James J. Kocsis

Part of the Monographs of the Physiological Society of Philadelphia book series (MPSP, volume 7)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Metabolism and Function of Taurine Analogues

    1. Front Matter
      Pages 1-3
    2. Heitaroh Iwata, Akemichi Baba, Satoru Yamagami
      Pages 21-29
    3. Akitane Mori, Yasuto Katayama, Isao Yokoi, Michiko Matsumoto
      Pages 41-48
    4. Back Matter
      Pages 67-67
  3. Actions of Taurine in the Central Nervous System

    1. Front Matter
      Pages 69-72
    2. Henry I. Yamamura, Robert C. Speth, Robert E. Hruska, Nereo Bresolin, Brad A. Meiners, Ryan J. Huxtable
      Pages 73-80
    3. Cheryl Nauss-Karol, Christina VanderWende
      Pages 81-91
    4. G. H. T. Wheler, H. F. Bradford, A. N. Davison, E. J. Thompson
      Pages 93-106
    5. G. H. T. Wheler, D. C. Klein
      Pages 107-121
    6. Elsa Kumpulainen, Anneli Karppinen, Kirsi-Marja Marnela, P. Lähdesmäki
      Pages 135-143
    7. M. J. Voaden, A. C. I. Oraedu, J. Marshall, N. Lake
      Pages 145-160
    8. H. Pasantes-Morales, R. M. Ademe, A. M. López-Colomé
      Pages 161-175
    9. John A. Sturman
      Pages 187-207
    10. Back Matter
      Pages 209-213
  4. Actions of Taurine in the Cardiovascular System

    1. Front Matter
      Pages 215-217
    2. Joel E. Shaffer, James J. Kocsis
      Pages 219-229
    3. Ryan J. Huxtable, Hugh E. Laird, Shirley Lippincott
      Pages 231-246
    4. J. Bahl, C. J. Frangakis, B. Larsen, S. Chang, D. Grosso, R. Bressler
      Pages 247-259
    5. S. W. Schaffer, J. Chovan, J. Kramer, E. Kulakowski
      Pages 261-279
    6. J. C. Khatter, P. L. Soni, R. J. Hoeschen, L. E. Alto, N. S. Dhalla
      Pages 281-293
    7. Ryuta Ito, Toshimitsu Uchiyama, Shuko Yoda, Noriaki Homma, Katsuo Furukawa
      Pages 313-327
    8. Back Matter
      Pages 329-335
  5. Clinical Implications of Taurine

    1. Front Matter
      Pages 337-339
    2. Kinya Kuriyama, Seitaro Ohkuma, Makoto Muramatsu
      Pages 341-362
    3. David K. Rassin, Gerald E. Gaull
      Pages 379-390
    4. Yukio Yamori, Yasuo Nara, Ryoichi Horie, Akira Ooshima, Walter Lovenberg
      Pages 391-403
    5. Steven I. Baskin, Colin M. Finney
      Pages 405-418
    6. J. B. Lombardini, M. F. Crass III
      Pages 419-436
    7. Back Matter
      Pages 437-440
  6. Back Matter
    Pages 441-446

About this book


It has become an annual custom for the Physiological Society of Philadel­ phia to sponsor a spring symposium in honor of A. N. Richards (\876-1966), a research pharmacologist who developed the classical micropuncture tech­ nique for studying kidney function. The A. N. Richards Symposium for 1979 was held on April 23-24 in Valley Forge, Pennsylvania. The theme of this symposium was "The Actions of Taurine on Excitable Tissues." Although taurine was discovered as a constituent of bile salts in 1857 by a chemist and an anatomist (Gmelin and Tiedemann), interest today centers chiefly on the extrahepatic actions of taurine, especially in brain, heart, and other excitable tissues. Research on taurine is clearly in a period of exponential growth. We can be sure that the research reports presented and described herein as the "Proceedings of the Symposium" will provide impetus for further growth. Thus the report describing macromolecular receptors for taurine in myocardial sarcolemma may provide a model for exploring the molecular mechanisms that underlie the action(s) of taurine. Stabilization of mem­ branes and modulation of ion fluxes are two fundamental actions of taurine dealt with in many of these reports. It is just these actions of taurine that have been reported by several investigators as being involved in human myotonia, diabetes, and heart failure.


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Editors and affiliations

  • S. W. Schaffer
    • 1
  • Steven I. Baskin
    • 2
  • James J. Kocsis
    • 3
  1. 1.Department of Physiology and BiophysicsHahnemann Medical CollegePhiladelphiaUSA
  2. 2.Department of PharmacologyMedical College of PennsylvaniaPhiladelphiaUSA
  3. 3.Department of PharmacologyJefferson Medical CollegePhiladelphiaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1981
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-009-8095-2
  • Online ISBN 978-94-009-8093-8
  • Buy this book on publisher's site