Myocardial Infarction

Measurement and Intervention

  • Galen S. Wagner

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 14)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Pathophysiology

    1. Front Matter
      Pages 1-1
    2. Grover M. Hutchins
      Pages 3-20
  3. Methods for Determining Infarct Size

    1. Front Matter
      Pages 21-21
    2. Ronald H. Selvester, Miguel E. Sanmarco, Joseph C. Solomon, Galen S. Wagner
      Pages 23-50
    3. Robert Roberts
      Pages 107-142
    4. William J. Rogers, Huey G. McDaniel, John A. Mantle, Silvio E. Papapietro, Richard O. Russell Jr., Charles E. Rackley
      Pages 159-172
    5. Victor S. Behar
      Pages 173-197
    6. Frans J. Th. Wackers, Harvey J. Berger, Barry L. Zaret
      Pages 199-233
    7. Richard S. Stack, Joseph Kisslo
      Pages 235-260
    8. J. William Whitaker, Erik L. Ritman
      Pages 261-276
    9. Frederick R. Cobb, Robert H. Murdock Jr., Kenneth G. Morris
      Pages 277-294
    10. Robert D. Okada, Charles A. Boucher, Gerald M. Pohost
      Pages 295-324
    11. Melvin L. Marcus, Raymundo T. Go, James C. Ehrhardt
      Pages 325-346
    12. Raymond E. Ideker, Donald B. Hackel, Eric C. McClees
      Pages 347-371
    13. John T. Fallon
      Pages 373-384
  4. Interventions for Limiting Infarct Size

    1. Front Matter
      Pages 385-385
    2. Keith A. Reimer
      Pages 387-395
    3. Keith A. Reimer, Robert B. Jennings
      Pages 397-414
    4. Lewis C. Becker
      Pages 415-456
    5. Thomas R. Griggs
      Pages 457-477
  5. An Overview

    1. Front Matter
      Pages 515-515
    2. James E. Muller, Robert E. Rude, Eugene Braunwald
      Pages 517-546
  6. Back Matter
    Pages 547-551

About this book


Patients currently experiencing acute myocardial infarcts are the beneficiaries of information gathered during the 80 years since this clinical phenomenon was described and the 20 years since treatment in coronary care units was introduced. Physicians have gained the ability to minimize inhospital mortality from rhythm disturbances and have gained insight into the importance of optimizing both left ventricular fIlling pressure and outflow resistance in the management of myocar­ dial failure. Understanding of the pathophysiology of acute myocardial infarcts has matured sufficiently so that now it is possible to consider whether an infarct must evolve to a predetermined size or whether the size could be limited by implementing one or more clinically feasible strategies. Concurrently, it has become evident that patients with acute infarcts are not as 'fragile' as previously supposed, and that they may undergo procedures such as coronary angiography and coronary bypass surgery with acceptable risks. Clinical trials are currently in progress to assess the possible benefit of various interventions for limiting myocardial infarct size. The outcome of these studies may be used to formulate strategies for clinical care of future patients. If the results are positive, community hospitals may undergo changes even more exten­ sive than those required when they established coronary care units. If the inter­ ventions are not proven to provide significant advantages over the course of nature, the current concepts of coronary care may be retained. However, such conclusions will be only as valid as the techniques used to measure infarct size.


blood energy imaging imaging techniques intervention myocardial infarction pathophysiology physiology therapy tomography ultrasound

Editors and affiliations

  • Galen S. Wagner
    • 1
  1. 1.Duke University Medical CenterDurhamUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1982
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-009-7454-8
  • Online ISBN 978-94-009-7452-4
  • Series Print ISSN 0166-9842
  • Buy this book on publisher's site