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Liver Metastasis

Basic aspects, detection and management

  • Cornelis J. H. Van De Velde
  • Paul H. Sugarbaker
Book

Part of the Developments in Oncology book series (DION, volume 24)

Table of contents

  1. Front Matter
    Pages I-XIV
  2. Basic Aspects of Liver Metastasis

  3. Diagnosis and Staging of Liver Metastases

  4. Treatment of Liver Metastases

    1. P. H. Sugarbaker, R. T. Ottow, D. A. August
      Pages 187-205
    2. S. Wallace, C. Charnsangavej, C. H. Carrasco, W. Bechtel, K. Wright, C. Gianturco
      Pages 214-229
    3. T. J. A. Kuijpers, A. T. van Oosterom, E. H. Overbosch, E. A. de Bruijn, M. Oudkerk
      Pages 230-248
  5. New Treatment Modalities

    1. P. D. Schneider, P. H. Sugarbaker, F. J. Gianola
      Pages 263-277
    2. Allan W. Wolkoff, Richard J. Stockert, Philip S. Schein
      Pages 278-291
    3. C. J. H. van de Velde, U. R. Tjaden, B. J. L. Kothuis
      Pages 292-312
    4. J. G. McVie, J. M. V. Burgers, C. Hoefnagel, E. Tomlinson
      Pages 313-323
  6. Surgical Techniques in the Management of Hepatic Metastases

    1. P. H. Sugarbaker, R. T. Ottow
      Pages 324-338
    2. P. H. Sugarbaker, P. D. Schneider
      Pages 339-345
    3. C. J. H. van de Velde, C. H. N. Veenhof, P. H. Sugarbaker
      Pages 358-373
  7. Back Matter
    Pages 374-383

About this book

Introduction

B. CADY Hepatic met,,'~tasl~S present one of the major therapeutic challenges of cancer patien: management, for it is the destruction of vital organ function that makes cancer fatal, not local tumor growth. The process of tumor cell dislodgement from the primary cancer, their spread through the lymphatic and hematogenous channels, their lodgement in distant sites, and their subsequent progressive growth tax our comprehension a'ld i. -ustrate our therapies. The proceedings of this International Con,t ss on Hepatic Metastasis address these aspects of metastases to t:'. >2 _ . ver, and predominatly focus on metastatic colon cancer because of t ~. s frequency, its prominent hepatic only pattern of spread, and enticing preliminary data about prevention and control of small sub­ . '(ts of the afflicted population. Predictably, the "false technologies" of Dr. Lewis Thomas that involve surgical, radiotherapeutic and chemo­ therapeutic attack on these metastases after elaborate diagnostic studies take precedence because of the clinical imperatives of sick patients. This is displayed in the preponderance of papers and in­ terest in various diagnostic scanning techniques by means of radio­ isotopes, radiographically useful dyes, biochemical markers, interest in developing accurate staging systems to categorize patients for therapeutic comparisons, and interest in elaborate, and expensive, technology to increase the effectiveness of chemotherap~utic agents that are of limited benefit with simple intravenous administration. Behind this clinical enthusiasm, however, lies the research to develop the "true technology," in Thomas' words, that will prevent such clinical catastrophies as hepatic metastases.

Keywords

Staging cell computed tomography (CT) imaging liver lymphoma magnetic resonance imaging (MRI) metastasis prevention radiotherapy screening surgery tumor

Editors and affiliations

  • Cornelis J. H. Van De Velde
    • 1
  • Paul H. Sugarbaker
    • 2
  1. 1.Department of SurgeryUniversity HospitalLeidenThe Netherlands
  2. 2.Colorectal Cancer SectionNational Institutes of HealthBethesdaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-009-6051-0
  • Copyright Information Springer Science+Business Media B.V. 1984
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-009-6053-4
  • Online ISBN 978-94-009-6051-0
  • Buy this book on publisher's site