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LHRH and Its Analogs

Contraceptive and Therapeutic Applications

  • Editors
  • B. H. Vickery
  • J. J. NestorJr.
  • E. S. E. Hafez
Book

Part of the Advances in Reproductive Health Care book series (ARHE, volume 1)

Table of contents

  1. Front Matter
    Pages i-xxix
  2. Chemistry and Basic Reproductive Properties

    1. Front Matter
      Pages 1-1
    2. J. J. Nestor Jr.
      Pages 3-10
    3. J. Rivier, C. Rivier, M. Perrin, J. Porter, W. Vale
      Pages 11-22
    4. J. J. Nestor Jr., T. L. Ho, R. Tahilramani, B. L. Horner, R. A. Simpson, G. H. Jones et al.
      Pages 23-33
  3. Reproductive Physiology and Pharmacology in Laboratory Animals

    1. Front Matter
      Pages 47-47
    2. D. W. Hahn, J. L. McGuire, W. Vale, J. Rivier
      Pages 49-60
    3. F. Bint Akhtar, E. J. Wickings, E. Nieschlag
      Pages 77-90
    4. B. H. Vickery, G. I. McRae
      Pages 91-106
    5. R. H. Asch, J. P. Balmaceda, M. Borghi
      Pages 107-123
    6. M. V. Nekola, D. H. Coy
      Pages 125-136
    7. G. I. McRae, B. H. Vickery, J. J. Nestor Jr., W. J. Bremner, T. M. Badger
      Pages 137-151
    8. D. Heber, R. S. Swerdloff
      Pages 153-160
  4. Extrahypophysial Parameters

    1. Front Matter
      Pages 161-161
    2. P. B. C. Jones, A. J. W. Hsueh
      Pages 163-179
    3. H. M. Fraser, R. M. Sharpe, R. M. Popkin
      Pages 181-195
    4. K. Sundaram, C. W. Bardin
      Pages 197-204
  5. Contraception in Women

    1. Front Matter
      Pages 205-205
    2. S. J. Nillius, C. Bergquist
      Pages 207-217
    3. A. Lemay, N. Faure, F. Labrie, A. T. A. Fazekas
      Pages 219-234
    4. W. Hardt, T. Genz, M. Schmidt-Gollwitzer
      Pages 235-242
    5. M. Schmidt-Gollwitzer, W. Hardt, K. Schmidt-Gollwitzer
      Pages 243-254
  6. Contraception in Men

    1. Front Matter
      Pages 255-255
    2. D. Heber, R. S. Swerdloff, M. Henzl
      Pages 257-269
    3. G. C. Doelle, R. M. Evans, A. N. Alexander, D. Rabin
      Pages 271-282
  7. Human Therapeutic Applications

    1. Front Matter
      Pages 283-283
    2. A. Hoffman, W. F. Crowley Jr.
      Pages 285-297
    3. F. Comite, G. B. Cutler Jr, D. L. Loriaux
      Pages 315-328
    4. H. A. Harvey, A. Lipton, D. T. Max
      Pages 329-335
    5. N. Faure, A. Lemay, G. Tolis, F. Labrie, A. Bélanger, A. T. A. Fazekas
      Pages 337-349
    6. R. J. Santen, B. Warner, L. M. Demers, M. Dufau, J. A. Smith Jr.
      Pages 351-364
  8. Diagnostic Applications of LHRH

    1. Front Matter
      Pages 365-365
    2. Z. Laron, R. Prager-Lewin, Z. Dickerman
      Pages 367-374
  9. Applications in Animals

    1. Front Matter
      Pages 375-375
    2. B. D. Schanbacher
      Pages 385-393
  10. Metabolic Parameters

    1. Front Matter
      Pages 395-395
    2. G. Flouret, M. A. Stetler-Stevenson, F. A. Carone, D. R. Peterson
      Pages 397-410
    3. J. Barron, E. Griffiths, G. Tsalacopoulos, R. P. Millar
      Pages 411-419
    4. S. T. Anik, L. M. Sanders, M. D. Chaplin, S. Kushinsky, C. Nerenberg
      Pages 421-435
  11. Perspectives

    1. Front Matter
      Pages 437-437
    2. M. J. K. Harper
      Pages 439-447
    3. R. A. Edgren, D. R. Shevlin
      Pages 449-457
    4. E. S. E. Hafez
      Pages 459-464
  12. Back Matter
    Pages 465-470

About this book

Introduction

A. CORBIN Investigations on LHRH and its analogs have just completed their first decade. We have witnessed a veritable explosion of chemical, physiologic and pharmacologic data on this hypothalamic peptide and the approximately 1500 agonist and antagonist analogs that have been synthesized. In order to track this expanding field, I was asked to organize an international symposium on basic and clinical aspects of LHRH analogs as part of the Reproductive Health Care: CDS Symposium held in Maui, Hawaii, in October 1982. This meeting brought together a number of the leading investigators in the field. Much new state-of-the-art information was presented which I and my colleagues felt deserved a wider audience. Drs Vickery, Nestor, and Hafez consented to undertake this task. Upon review of the literature, it was apparent that there was no recent text which fully covered the breadth of developments in the field. Accordingly, the editors decided to use the symposium as a nucleus on which to build a singular, comprehensive state-of-the-art analysis of this rapidly growing discipline, and the application of such knowledge to reproductive medicine. As exemplified by the various areas of expertise provided by the individual contributors, it becomes obvious that the scope of the subject matter, while relating solely to a well-defined chemical class (LHRH analogs) and a circumscribed physiologic and pharmacologic entity (reproduction), has expanded enormously.

Keywords

contraception fertility infertility metabolism regulation

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-009-5588-2
  • Copyright Information Springer Science+Business Media B.V. 1984
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-8963-0
  • Online ISBN 978-94-009-5588-2
  • Buy this book on publisher's site