Mononuclear Phagocytes

Characteristics, Physiology and Function

  • Ralph van Furth

Table of contents

  1. Front Matter
    Pages III-XXII
  2. Surface Properties of Mononuclear Phagocytes

    1. Front Matter
      Pages 1-1
    2. R. F. Todd III, A. Biondi, J. A. Roach
      Pages 31-40
    3. P. H. Nibbering, P. C. J. Leijh, R. van Furth
      Pages 49-58
    4. P. D. Stahl, T. E. Wileman, V. L. Shepherd
      Pages 59-66
    5. J. Aggeler, R. Takemura, B. A. Nichols, Z. Werb
      Pages 87-98
    6. L. A. Ginsel, R. de Water, J. W. M. van der Meer, W. Th. Daems
      Pages 99-113
    7. T. A. Springer, L. Sastre, F. Schmalstieg, D. Anderson
      Pages 115-123
  3. Interactions of Complement with Membranes of Mononuclear Phagocytes

  4. In Vivo Kinetics and in Vitro Growth of Mononuclear Phagocytes

    1. Front Matter
      Pages 199-199
    2. R. van Furth, M. M. C. Diesselhoff-den Dulk, W. Sluiter, J. T. van Dissel
      Pages 201-210
    3. C. W. Pugh, G. G. MacPherson
      Pages 211-220
    4. E. H. Burger, J. W. M. van der Meer, F. P. van de Wijngaert, R. van Furth
      Pages 221-231
    5. J. W. M. van der Meer, J. S. van de Gevel, R. de Water, L. A. Ginsel, C. H. Wouters, W. Th. Daems et al.
      Pages 243-254
    6. C. C. Stewart, E. B. Walker, C. Johnson, R. Little
      Pages 255-266
  5. Secretion of Products by Mononuclear Phagocytes

    1. Front Matter
      Pages 267-267
    2. Z. Werb, J. R. Chin, R. Takemura, S. M. Frisch, R. L. Oropeza, D. F. Bainton
      Pages 269-278
    3. E. M. Mahoney, J. C. Khoo, J. L. Witztum, D. Steinberg
      Pages 279-285
    4. J. J. Oppenheim, K. Onozaki, K. Matsushima
      Pages 287-293
    5. A. A. Aderem, W. A. Scott, Z. A. Cohn
      Pages 311-318
    6. J. Schnyder, V. Evêquoz, U. Trechsel, M. Baggiolini
      Pages 319-326
  6. Mobilization and Chemotaxis of Mononuclear Phagocytes

  7. Membrane Electrophysiology of Mononuclear Phagocytes

  8. Intra- and Extracellular Cytotoxicity of Mononuclear Phagocytes

    1. Front Matter
      Pages 409-409

About this book


Sixteen years have passed since the first Leiden Conference on Mononuclear Phagocytes. That first meeting led to new nomenclature, i. e. , the Mononuclear Phagocytes System (MPS), which was published in the Bulletin of the World Health Organization (R. van Furth, et aI. , Bull. WHO, 1972, 46: 845-852). The paradigm of the MPS has the advantage of being much more consistent than the Reticuloendothelial System (RES) (L. Aschoff, Ergebn. Inn. Med. Kinderheilk. 1924, 26:1), because cells with similar characteristics can be classified in the same category. The essence ota new concept is, according to Popper, that it must be susceptible to falsification. This has been attempted several times for the MPS by those who adhere to the RES. However, in biology no one can be certain of truth. Any theory must be based on experimental observations and/or theoretical consider­ ations and both should be presented in such a way that others can try to refute it, then or later. One may have a theoretical or a pragmatic preference for a theory which at a given time is regarded as possibly truc, but later it may be shown to be false. In other words, what we present in this volume is regarded as true at this moment, but others may consider it as not true and try to disprove it. Controversies often stimulate new research.


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Editors and affiliations

  • Ralph van Furth
    • 1
  1. 1.Department of Infectious DiseasesUniversity HospitalLeidenThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1985
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-8723-0
  • Online ISBN 978-94-009-5020-7
  • Buy this book on publisher's site