Coronary Angioplasty: A Controlled Model for Ischemia

  • P. W. Serruys
  • G. T. Meester

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 58)

Table of contents

  1. Front Matter
    Pages I-XIX
  2. Guy R. Heyndrickx, Stephen F. Vatner
    Pages 1-18
  3. Patrick W. Serruys, Brian Jaski, Federico Piscione, Folkert ten Kate, Pim de Feyter, Marcel van den Brand et al.
    Pages 19-31
  4. Bernhard Meier, Wilhelm Rutishauser
    Pages 33-37
  5. R. Erbel, B. Henkel, G. Schreiner, W. Clas, R. Brennecke, H. Kopp et al.
    Pages 39-53
  6. Patrick W. Serruys, Federico Piscione, William Wijns, Johan A. J. Hegge, Eef Harmsen, Marcel van den Brand et al.
    Pages 77-94
  7. Michel E. Bertrand, Jean M. Lablanche, Jean L. Fourrier, Giles Traisnel
    Pages 133-139
  8. M. Grbic, U. Sigwart
    Pages 141-149
  9. Patrick W. Serruys, Federico Piscione, William Wijns, Cees Slager, Pim de Feyter, Marcel van den Brand et al.
    Pages 151-188

About this book


Since the introduction of coronary angioplasty in 1977, this procedure has gained a steadily increasing position in the treatment of coronary artery obstmction. From the available evidence it can be estimated, that this thera­ peutic tool will get even more additional momentum of many ten-thousands of patients to be treated in the next few years, due to a growing fraction of patients who are candidates for this intervention. Information about the indications, benefits and risks of coronary angioplasty is accumulating rapidly in addition to publications about refinements of the technique itself. Recently, a number of investigators have realized that coronary angioplasty is not only a therapeutic tool, but can, during the procedure, be used as a source of diagnostic information. When the catheter is placed in a coronary artery obstruction, inflation of the balloon produces transient myocardial ischemia. Before, during, and after this period of severe ischemia, studies of the perfor­ mance of the myocardium at risk can be carried out. The fact that therapeutic coronary angioplasty is carried out in a cardiac catheterization laboratory which is by definition optimally equipped for the measurement of hemodynamic parameters, has probably also contributed to the effectuation of these investigations. The combination of hemodynamic and biochemical parameters with morphological information from the coronary angiogram can be utilized for the quantification of myocardial involvement and the success of coronary dilatation with angioplasty. Studies of interactions with pharmacological substances are also feasible and informative.


PTCA angiography circulation coronary artery disease echocardiography electrocardiogram (ECG) hemodynamics

Editors and affiliations

  • P. W. Serruys
    • 1
  • G. T. Meester
    • 2
  1. 1.Thorax CenterErasmus UniversityRotterdamThe Netherlands
  2. 2.Erasmus UniversityRotterdamThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Martinus Nijhoff Publishers, Dordrecht 1986
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-8409-3
  • Online ISBN 978-94-009-4295-0
  • Series Print ISSN 0166-9842
  • Buy this book on publisher's site