Immunology of Eye Diseases

  • Susan Lightman

Part of the Immunology and Medicine Series book series (IMME, volume 13)

Table of contents

  1. Front Matter
    Pages i-xi
  2. D. A. Brewerton
    Pages 1-8
  3. M. G. Falcon
    Pages 41-60
  4. S. Lightman, C.-C. Chan
    Pages 87-99
  5. D. A. Francis, W. I. McDonald
    Pages 101-120
  6. A. Garner, A. McCartney
    Pages 121-143
  7. K. Fairburn, D. A. Isenberg
    Pages 145-166
  8. Back Matter
    Pages 167-171

About this book


The eye can become involved in immune-mediated diseases that affect it alone or as part of a multi-organ disease process. Much immunological attention has been focused on other organs affected by these processes and the subject of the immunology of eye diseases is a relatively new one. Many of these diseases that involve the eye are not life-threatening but can result in devastat­ ing loss of sight that if bilateral, will have major effects on the patient's life. Systemic immunological investigations are generally unhelpful in these patients and one of the major problems in this field has been the lack of diseased tissue available for examination to determine the pathological processes involved. Our poor understanding of basic mechanisms of disease in the eye has meant that treatment of many of these conditions is often inadequate. It has become possible to apply in the eye many ofthe techniques used to investigate the role of the immune system in other systems. Animal models of many of the disease processes have also allowed dissection of the immune response both within and outside the eye. It is my belief that a greater understanding of the mechanisms by which the structures in the eye become damaged will allow more specific and effective therapeutic strategies to be devised.


diseases eye genetics pathology transplantation virus

Editors and affiliations

  • Susan Lightman
    • 1
  1. 1.Institute of OphthalmologyUniversity of LondonLondonUK

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1989
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-7623-4
  • Online ISBN 978-94-009-2490-1
  • Buy this book on publisher's site