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The Importance of Animal Experimentation for Safety and Biomedical Research

  • S. Garattini
  • D. W. van Bekkum

Table of contents

  1. Front Matter
    Pages i-vii
  2. The necessity of animal experimentation

    1. Silvio Garattini
      Pages 1-3
  3. Ethical and Legal Aspects

  4. Recent Progress of Medicine Requiring the Use of Animals

    1. Front Matter
      Pages 47-47
    2. Alfredo Gorio, Flaminio Cattabeni
      Pages 57-69
    3. D. Ganten, K. Lindpaintner, Th. Unger, J. Mullins
      Pages 89-96
    4. Giovanni de Gaetano, Chiara Cerletti, Andreina Poggi, Maria Benedetta Donati
      Pages 97-109
    5. Carla Zoja, Norberto Perico, Giuseppe Remuzzi
      Pages 111-123
    6. Guido Forni, Patrizia Caretto, Paola Ferraiorni, Maria Carla Bosco, Mirella Giovarelli
      Pages 125-132
    7. T. A. Connors
      Pages 133-140
    8. Peter Bentvelzen
      Pages 153-161
  5. Use of Animals for Safety Reasons

  6. The Future of Animal Research

    1. Front Matter
      Pages 211-211
    2. Mara Rossini, Elisabetta Di Martino, Giuliano Bensi
      Pages 213-221
    3. Martin Kramer
      Pages 237-246

About this book

Introduction

Scientists are coming under increasing pressure from activist groups to stop animal experimentation, branded as cruel and unnecessary for improving human health. This attitude, however, stems from an unrealistic evaluation of the situation and distorted information about present scientific knowledge. There is no question that most medical progress - perhaps all, in fac- has been attained through knowledge derived initially from experiments in various animal species. There is practically no way of replacing animals in these investigations and so-called 'alternative methods' are in reality merely complementary. Tissue cultures, cell, microorganisms, enzymes, membranes, mathematical models - all are useful for preliminary screening tests and for testing hypotheses, but the complexity of a living organism is such that in vivo studies are essential before any test can responsibly be made in man. This book presents the proceedings of an international symposium organized in Strasbourg (October 24-25, 1988), with the aim of assessing present-day requirements as regards animal experimentation in research related to major medical and toxicological problems still awaiting solutions.

Keywords

AIDS Laboratory Tumor biology gene therapy transplantation

Editors and affiliations

  • S. Garattini
    • 1
  • D. W. van Bekkum
    • 2
  1. 1.Pharmacological Research Institute ‘Mario Negri’MilanItaly
  2. 2.Radiobiological Institute ‘TNO’RijswijkThe Netherlands

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-009-1904-4
  • Copyright Information Springer Science+Business Media B.V. 1990
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-7349-3
  • Online ISBN 978-94-009-1904-4
  • Buy this book on publisher's site