Fundamental Aspects of Cancer

  • Ronald H. Goldfarb

Part of the Cancer Growth and Progression book series (CAGP, volume 1)

Table of contents

  1. Front Matter
    Pages i-x
  2. Ronald H. Goldfarb, Kenneth W. Brunson
    Pages 28-32
  3. H. E. Kaiser
    Pages 33-34
  4. H. E. Kaiser, J. Paradiso, M. Jones
    Pages 35-40
  5. James Varani, J. Philip McCoy, Peter A. Ward
    Pages 73-83
  6. Peter A. Netland, Bruce R. Zetter
    Pages 84-97
  7. E. L. Gorelik, R. B. Herberman
    Pages 134-143
  8. Gregory A. Curt, Bruce A. Chabner
    Pages 162-170
  9. Takao Ohnuma, James F. Holland
    Pages 171-191
  10. Vincent A. Pollack
    Pages 192-200
  11. Back Matter
    Pages 201-211

About this book


Individual neoplastic diseases often show discrete growth direct effect of tumor metastases or to adverse consequences patterns subject to many modifications according to the associated with these therapeutic modes (e.g., complications stage of the disease, the species involved and the tumor type of immunosuppression which can lead to mortality arising concerned. Primary neoplasms are less difficult to treat in from infectious disease). contrast to secondary neoplasms. The chief type of secon­ It is therefore quite clear that there is a crucial need for dary neoplastic growth, metastasis, is also comparatively new methods for the detection of micrometastases and the development of new modalities for the treatment of estab­ less well understood. Phylogenetically, metastasis attains its highest level of development in the mammal and is best lished metastases. It is likely that such modalities must known in man, but is still far from being understood. overcome tumor heterogeneity and drug resistance to yield new therapeutic modalities with improved margin of safety The process of cancer growth and progression, from the initiation of neoplastic transformation of normal cells to the and efficacy over currently available anti-neoplastic drugs.



Editors and affiliations

  • Ronald H. Goldfarb
    • 1
    • 2
  1. 1.Pittsburgh Cancer InstitutePittsburghUSA
  2. 2.Department of PathologyUniversity of Pittsburgh, School of MedicinePittsburghUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1989
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-6980-9
  • Online ISBN 978-94-009-1089-8
  • Buy this book on publisher's site