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The Search for New Anticancer Drugs

  • M. J. Waring
  • B. A. J. Ponder

Part of the Cancer Biology and Medicine book series (CABM, volume 3)

About this book

Introduction

Most of the anti-cancer drugs in use today were discovered by happy accident rather than design, yet the rational design of better anti-cancer drugs remains a cherished goal, and one of the most important challenges facing medical science.
This book represents a compilation of views and progress reports which illustrate the diversity of approaches to the problem. Recent research has confirmed the belief that critical genetic changes are at work in cancer cells. The genome, then (DNA in biochemical terms), surely represents a critical target for specific chemotherapy of cancer, and several chapters address the issue of attacking DNA, gene targetting, and the like. Others deal with principles of rational design, exploitation of novel modalities and targets, or the nuts and bolts of antitumour drug testing. While no attempt has been made to provide a comprehensive coverage of this wide-ranging and vitally important subject, the present volume in the series will provide much food for thought.

Keywords

DNA cancer chemistry chemotherapy drug drug design lead medicinal chemistry research tumor

Editors and affiliations

  • M. J. Waring
    • 1
  • B. A. J. Ponder
    • 2
  1. 1.University of CambridgeUK
  2. 2.CRC Human Cancer Genetics Research Group, Department of PathologyUniversity of CambridgeUK

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-009-0385-2
  • Copyright Information Springer Science+Business Media B.V. 1992
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-6659-4
  • Online ISBN 978-94-009-0385-2
  • Series Print ISSN 0928-8945
  • Buy this book on publisher's site