Inflammatory Bowel Disease

Basic Research, Clinical Implications and Trends in Therapy

  • L. R. Sutherland
  • S. M. Collins
  • F. Martin
  • R. S. McLeod
  • S. R. Targan
  • J. L. Wallace
  • C. N. Williams

Table of contents

  1. Front Matter
    Pages i-xv
  2. Basic Research and Clinical Implications in IBD

    1. Front Matter
      Pages 1-1
    2. Predisposing factors in the etiology of IBD: what we can learn from animal models

    3. Predisposing factors in the etiology of IBD: bugs, drugs and leaks

      1. I. Bjarnason, A. Macpherson, I. S. Menzies
        Pages 53-70
    4. Predisposing factors in the etiology of IBD: is there a primary immune defect?

      1. G. S. Eisenbarth
        Pages 73-80
      2. C. O. Elson, R. P. McCabe Jr, K. W. Beagley, A. Sharmanov, S. L. Brandwein, B. U. Ridwan et al.
        Pages 81-87
      3. K. Croitoru, D. K. H. Wong, M. E. Baca-Estrada
        Pages 88-95
      4. J. Braun, Y. Valles-Ayoub, L. Berberian, M. Eggena, L. K. Gordon, S. Targan
        Pages 96-103
    5. Pathophysiology of intestinal inflammation: intracellular and intercellular signalling

      1. N. A. Wright
        Pages 107-120
      2. M. B. Grisham, S. Aiko, T. E. Zimmerman
        Pages 121-126
    6. Pathophysiology of intestinal inflammation: symptom generation in IBD

      1. K. E. Barrett
        Pages 129-138
      2. M. H. Perdue
        Pages 139-148
      3. K. A. Sharkey, E. J. Parr
        Pages 149-161
      4. S. M. Collins, I. Khan, B. Vallance, C. Hogaboam
        Pages 162-169
  3. Trends in IBD Therapy 1994

    1. Front Matter
      Pages 181-181
    2. Critical appraisal of clinical trials

      1. L. R. Sutherland
        Pages 185-190
      2. E. J. Irvine
        Pages 191-196
      3. G. W. Whiting, J. Lau, B. Kupelnick, T. C. Chalmers
        Pages 203-217
    3. Basic science: genetics, markers and models

    4. Basic science: pathogenesis

      1. C. Fiocchi
        Pages 243-261
      2. S. M. Collins, H. P. Weingarten, K. McHugh
        Pages 262-267
    5. Surgical issues in IBD

    6. Lifestyle in IBD

      1. C. Benoni
        Pages 319-327
      2. K. N. Jeejeebhoy
        Pages 328-331
      3. R. G. Farmer
        Pages 338-344
      4. I. T. Beck, D. J. Leddin, S. E. Lemire, E. A. Shaffer, L. R. Sutherland, A. B. R. Thomson et al.
        Pages 345-357
    7. Therapeutics

      1. C. N. Williams
        Pages 361-366
      2. F. Shanahan, G. C. O’Sullivan, J. K. Collins
        Pages 367-373
    8. Therapy in IBD in 1994

  4. Back Matter
    Pages 433-443

About this book


The inflammatory bowel diseases, of unknown etiology and for which there are no cures, continue to attract the attention and interest of gastroenterologists, internists and surgeons. International symposia are common and it is safe to say that there is at least one major symposium held somewhere in the world each year. This book encompasses the proceedings of two recent symposia held in Victoria, British Columbia, Canada. The symposia were the fifth and sixth international meetings focused on inflammatory bowel disease in Canada in the last eight years. Once again they were sponsored by Axcan Pharma, Inc. (formerly Interfalk Canada, Inc.) and endorsed by the Canadian Association of Gastroenterology. As has become traditional at such meetings the faculty was drawn from an international roster ofleaders in the field of inflammatory bowel disease and gastroenterology. The chapters of the proceedings provide a timely, up-to-date review of the major issues, including those within the realm of basic science and others dealing with clinical problems. The first symposium, 'Basic Research and Clinical Implications', was co-ordinated by John Wallace in association with Stephen Collins and Stephan Targan. The themes of this section were organized under the general topics of predisposing factors (genetics, animal models, infection, permeability, and immune deficits) and the pathophysiology of intestinal inflammation. The second symposium, Trends in Therapy' was organized by Lloyd Sutherland along with Franc;:ois Martin, Robin McLeod and Noel Williams.


cancer gastroenterology inflammation muscle nutrition pathophysiology physiology surgery

Editors and affiliations

  • L. R. Sutherland
    • 1
  • S. M. Collins
    • 2
  • F. Martin
    • 3
  • R. S. McLeod
    • 4
  • S. R. Targan
    • 5
  • J. L. Wallace
    • 6
  • C. N. Williams
    • 7
    • 8
  1. 1.Division of GastroenterologyThe University of CalgaryCanada
  2. 2.Division of GastroenterologyMcMaster University, Faculty of Health SciencesHamiltonCanada
  3. 3.Division of GastroenterologySt Luc HospitalMontrealCanada
  4. 4.Department of SurgeryUniversity of Toronto, Mount Sinai HospitalTorontoCanada
  5. 5.Inflammatory Bowel Disease CenterCedars-Sinai Medical CenterLos AngelesUSA
  6. 6.Health Sciences CenterUniversity of CalgaryCalgaryCanada
  7. 7.Division of GastroenterologyDalhousie UniversityHalifax, Nova ScotiaCanada
  8. 8.Faculty of MedicineClinical Research CenterHalifax, Nova ScotiaCanada

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1994
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-6653-2
  • Online ISBN 978-94-009-0371-5
  • Buy this book on publisher's site