Lipid-Lowering Therapy and Progression of Coronary Atherosclerosis

  • Albert V. G. Bruschke
  • Johan H. C. Reiber
  • K. I. Lie
  • Hein J. J. Wellens

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 180)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Mechanisms of normal progression and regression

    1. Front Matter
      Pages 1-1
    2. H. Buchwald, C. T. Campos
      Pages 17-28
  3. Methodological aspects of angiographic trials

    1. Front Matter
      Pages 29-29
    2. J. H. C. Reiber, J. W. Jukema, G. Koning, A. V. G. Bruschke
      Pages 45-63
    3. L. Cashin-Hemphill
      Pages 65-70
    4. A. V. G. Bruschke, J. W. Jukema, A. J. Van Boven, E. T. Bal, J. H. C. Reiber, A. H. Zwinderman
      Pages 71-77
  4. Angiographic lipid-lowering clinical trials

    1. Front Matter
      Pages 79-79
    2. J. W. Jukema, A. J. Van Boven, J. H. C. Reiber, A. H. Zwinderman, K. I. Lie, A. V. G. Bruschke
      Pages 85-106
    3. V. M. G. Maher
      Pages 107-113
    4. The Maas Investigators
      Pages 119-130
    5. E. L. Alderman, A. McMillan, W. Haskell
      Pages 151-165
    6. C. M. Gibson, P. H. Stone, R. C. Pasternak, F. M. Sacks, Harvard Atherosclerosis Reversibility Project Group
      Pages 179-191
    7. L. Campeau, G. Knatterud, C. White, M. Domanski, N. L. Geller, Y. Rosenberg et al.
      Pages 203-213
    8. H. J. J. Wellens, A. V. G. Bruschke
      Pages 215-217
  5. Back Matter
    Pages 219-230

About this book


A unique overview of all major angiographic lipid intervention trials, presented by their principal investigators. Basic mechanisms and methodological aspects, including biochemical as well as angiographic aspects, are discussed by experts in these fields. A careful comparison of all available data permits an analysis to be made of what may currently be considered proved, which aspects merit further investigation, and which hypotheses should be rejected.
Audience: Clinicians involved in the practice of lipid lowering and investigators involved in lipid-lowering clinical trials. Scientists involved in other areas of lipid research and investigators conducting coronary angiographic trials designed to study the influence of different interventions will find a wealth of information and practical guidelines in this book.


Bypass Lipoprotein atherosclerosis coronary artery disease coronary heart disease

Editors and affiliations

  • Albert V. G. Bruschke
    • 1
  • Johan H. C. Reiber
    • 2
  • K. I. Lie
    • 3
  • Hein J. J. Wellens
    • 4
  1. 1.Department of CardiologyUniversity Hospital LeidenLeidenThe Netherlands
  2. 2.Department of Diagnostic Radiology and Nuclear MedicineUniversity Hospital LeidenLeidenThe Netherlands
  3. 3.University of AmsterdamThe Netherlands
  4. 4.Interuniversity Cardiology Institute of The NetherlandsUtrechtThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1996
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-6551-1
  • Online ISBN 978-94-009-0143-8
  • Series Print ISSN 0166-9842
  • Buy this book on publisher's site