Tumors of the Central Nervous System, Volume 12

Molecular Mechanisms, Children's Cancer, Treatments, and Radiosurgery

  • M.A. Hayat

Part of the Tumors of the Central Nervous System book series (TCNS, volume 12)

Table of contents

  1. Front Matter
    Pages i-xlviii
  2. Molecular Mechanisms

    1. Front Matter
      Pages 1-1
    2. Nicolas Caron, Emmanuelle C. Genin, Renaud Vandenbosch, Pierre Beukelaers, Laurent Nguyen, Brigitte Malgrange
      Pages 19-32
    3. Maria Ines, Perez Millán, Carolina Cristina, Silvia Inés Berner, Damasia Becu-Villalobos
      Pages 33-41
    4. Beatrice Nico, Simona Ruggieri, Domenico Ribatti
      Pages 43-50
    5. Antonella Poloni, Giulia Maurizi
      Pages 51-60
  3. Children’s Cancer

    1. Front Matter
      Pages 61-61
    2. Yasmin Lassen-Ramshad, Jørgen B. Petersen, Akmal Safwat, Henrik Pagh Schultz, Morten Høyer
      Pages 91-106
    3. Mustafa Nadi, Claudia Faria, James T. Rutka
      Pages 107-119
    4. Lucie M. Turcotte, Joseph P. Neglia
      Pages 137-145
  4. Treatments

    1. Front Matter
      Pages 147-147
    2. Stefan Bauer, Roland Wiest, Johannes Slotboom, Mauricio Reyes
      Pages 159-169
    3. Paulo A. Garcia, John H. Rossmeisl Jr., Thomas L. Ellis, Rafael V. Davalos
      Pages 171-182
    4. Melvin Omodon, Steven Kalkanis
      Pages 183-189
    5. Torstein R. Meling, Benjamin Lassen, Eirik Helseth
      Pages 191-200
    6. Leo F. S. Ditzel Filho, Nancy McLaughlin, Domenico Solari, Daniel M. Prevedello, Amin B. Kassam, Ricardo L. Carrau et al.
      Pages 201-211
    7. Giuseppe Talamonti, Giuseppe D’Aliberti, Alberto Debernardi
      Pages 213-225
    8. Torstein R. Meling, Benjamin Lassen, Eirik Helseth
      Pages 227-233
    9. Garni Barkhoudarian, Aaron Cutler, Daniel F. Kelly
      Pages 235-245
    10. Mette Linnert, Birgit Agerholm-Larsen, Faisal Mahmood, Helle K. Iversen, Julie Gehl
      Pages 247-259
    11. Donald S. Backos, Robyn L. Poerschke, Christopher C. Franklin, Philip Reigan
      Pages 277-290
    12. Lauren Nye, Timothy Huyck, Jeffrey Raizer
      Pages 291-299
  5. Radiosurgery

    1. Front Matter
      Pages 313-313
    2. Karen Huscher, Pantaleo Romanelli
      Pages 315-320
    3. Pantaleo Romanelli, Alfredo Conti
      Pages 321-333
    4. Pantaleo Romanelli, Alfredo Conti
      Pages 335-343
    5. Siavash Jabbari, Lijun Ma, Paul Sanghera, Eric L. Chang, Sam T. Chao, Alex Karotki et al.
      Pages 345-357
    6. Fraser C. Henderson Sr., Kyle McCool, Juliet Seigle, Gregory J. Gagnon
      Pages 359-368
  6. M. A. Hayat
    Pages E1-E1
  7. Back Matter
    Pages 369-386

About this book


As in the case of its eleven predecessors in the series Tumors of the Central Nervous System, this volume is distinguished for its thorough approach, its roster of 92 distinguished contributors representing 11 different countries and its detailed examination of leading-edge technology and methods.

Volume 12: Molecular Mechanisms, Children’s Cancer, Treatments, and Radiosurgery offers a comprehensive review of the diagnosis, therapy and prognosis of brain and spinal cord tumors. Coverage extends to a large number of tumor types, including neuroblastoma, medulloblastoma, meningioma and chordoma. Molecular profiling of brain tumors to select appropriate therapy in clinical trials of brain tumors is discussed in detail, as is the classification/diagnosis of brain tumors based on function analysis. CDK6 as the molecular regulator of neuronal differentiation in the adult brain, and the role of aquaporins in human brain tumor growth are explained. Discussion also includes tumors affecting children, including neuroblastoma and medulloblastoma. A full chapter is devoted to the role of molecular genetic alterations in medulloblastoma, and another examines survival differences between children and adults with medulloblastoma. The use of various types of imaging methods to diagnose brain tumors is explained. In-depth discussion of treatment options includes stereotactic radiosurgery, endoscopic neurosurgery, electrochemotherapy, transsphenoidal surgery, focal ablation, whole brain radiation therapy and recraniotomy.


Cancer diagnosis Cancer therapy Imaging methods Pediatric tumors Stereotactic radiosurgery

Editors and affiliations

  • M.A. Hayat
    • 1
  1. 1.Department of Biological SciencesKean University, Room 213, Library BuildingUnionUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media Dordrecht 2014
  • Publisher Name Springer, Dordrecht
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-94-007-7216-8
  • Online ISBN 978-94-007-7217-5
  • Series Print ISSN 2215-096X
  • Series Online ISSN 2215-0978
  • Buy this book on publisher's site