Role of Capsaicin in Oxidative Stress and Cancer

  • Sanjay K. Srivastava

Part of the Diet and Cancer book series (DICA, volume 3)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Kartick C. Pramanik, Sanjay K. Srivastava
    Pages 1-18
  3. Giorgio Santoni, Sara Caprodossi, Valerio Farfariello, Sonia Liberati, Consuelo Amantini
    Pages 19-46
  4. Inés Díaz-Laviada
    Pages 47-65
  5. Robert S. Svatek, Rita Ghosh
    Pages 67-87
  6. Wanying Zhang, Jie Liao, Haonan Li, Allison Yang, Sanjay K. Srivastava, Guang-Yu Yang
    Pages 89-106
  7. Kartick C. Pramanik, Palika Datta, Sanjay K. Srivastava
    Pages 149-171
  8. Back Matter
    Pages 173-178

About this book

Introduction

Capsaicin is a principal pungent ingredient of red chili peppers, first isolated in the early nineteenth century by Christian Friedrich Bucholz. Widely consumed as a spice in South Asia and Latin America, Capsaicin has been used to treat pain and inflammation associated with a variety of diseases, including rheumatoid arthritis, diabetic neuropathy, post-masectomy pain, cluster headaches, and herpes zoster. Although recent studies have evaluated capsaicin as a novel anti-cancer agent, and mechanisms of capsaicin in preventing cancer have been described sporadically, the literature lacks a comprehensive review of capsaicin as a chemo-preventive agent.

Role of Capsaicin in Oxidative Stress and Cancer offers a thorough exploration of the preventive and therapeutic effects of capsaicin in cancer models such as melanoma, pancreatic cancer, colon cancer, gastric cancer, breast cancer, prostate cancer, skin cancer, lung cancer, multiple myeloma and glioma. 

The contributors, all internationally recognized researchers, identify various molecular and cellular targets of capsaicin, and show the critical role of mitochondria in capsaicin-mediated therapeutic effects. Readers will learn how capsaicin prevents or may treat cancer, how different cells respond to capsaicin, how environmental carcinogen-induced carcinogenesis can be prevented by capsaicin and the mechanism of oxidative stress caused by capsaicin.  This book will benefit medical students, oncologists and cancer researchers everywhere.

Keywords

Cancer Capsaicin Oxidative stress Prevention Therapy

Editors and affiliations

  • Sanjay K. Srivastava
    • 1
  1. 1., Biomedical SciencesTexas Tech Univ. Health Sciences CenterAmarilloUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-007-6317-3
  • Copyright Information Springer Science+Business Media Dordrecht 2013
  • Publisher Name Springer, Dordrecht
  • eBook Packages Medicine
  • Print ISBN 978-94-007-6316-6
  • Online ISBN 978-94-007-6317-3
  • About this book