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Glioma Signaling

  • Jolanta Barańska

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 986)

Table of contents

  1. Front Matter
    Pages i-x
  2. Stefania Ceruti, Maria P. Abbracchio
    Pages 13-30
  3. Dorota Wypych, Jolanta Barańska
    Pages 31-59
  4. Elizandra Braganhol, Márcia Rosângela Wink, Guido Lenz, Ana Maria Oliveira Battastini
    Pages 81-102
  5. Wanda Kłopocka, Jarosław Korczyński, Paweł Pomorski
    Pages 103-119
  6. Aneta Kwiatkowska, Marc Symons
    Pages 121-141
  7. Mitsutoshi Nakada, Daisuke Kita, Lei Teng, Ilya V. Pyko, Takuya Watanabe, Yutaka Hayashi et al.
    Pages 143-170
  8. Bozena Kaminska, Marta Kocyk, Magdalena Kijewska
    Pages 171-187
  9. Karolina Swiatek-Machado, Bozena Kaminska
    Pages 189-208
  10. Aleksandra Ellert-Miklaszewska, Iwona Ciechomska, Bozena Kaminska
    Pages 209-220
  11. Back Matter
    Pages 221-227

About this book

Introduction

Gliomas, developing in the brain from the transformed glial cells, are a very special kind of tumors, extremely refractory to conventional treatments. Therefore, for the development of new antitumor strategies, a better understanding of molecular mechanisms responsible for their biology, growth and invasion is still needed. Glioma Signaling is a text reference on cellular signaling processes regulating gliomas physiology and invasiveness. The first half of the book is focused on the mechanism of nucleotide receptor activation by exogenous nucleotides. The remaining chapters deal with the formation of complex signaling cascades, including cytoplasmic transcription factors, induced by growth factors, cytokines and cannabinoids. The book provides a framework explaining how signal transduction elements may modulate glioma cytoskeleton structure, cytoplasmic calcium concentration, cellular growth, progression and invasion, as well as presents perspectives concerning potential targets for glioma therapy.

Keywords

gliomas signaling nucleotide receptors tumor growth tumor invasion tyrosine kinase receptors

Editors and affiliations

  • Jolanta Barańska
    • 1
  1. 1., BiochemistryNencki Institute of Experimental BiologyWarsawPoland

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-007-4719-7
  • Copyright Information Springer Science+Business Media Dordrecht 2013
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-94-007-4718-0
  • Online ISBN 978-94-007-4719-7
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site