Innovation in Vaccinology

from design, through to delivery and testing

  • Selene Baschieri

Table of contents

  1. Front Matter
    Pages i-xii
  2. Vaccine Design

    1. Front Matter
      Pages 1-1
    2. Laura Serino, Kate L. Seib, Mariagrazia Pizza
      Pages 3-15
  3. Vaccine Delivery

    1. Front Matter
      Pages 43-43
    2. Silvia Loureiro, Elena Robinson, Hongying Chen, Pongsathon Phapugrangkul, Camilo Colaco, Ian M Jones
      Pages 45-63
    3. Antonella Folgori, Stefania Capone
      Pages 65-86
    4. Rossella Sartorius, Domenico Russo, Luciana D’Apice, Piergiuseppe De Berardinis
      Pages 123-134
    5. Chiara Lico, Carla Marusic, Floriana Capuano, Giampaolo Buriani, Eugenio Benvenuto, Selene Baschieri
      Pages 179-203
    6. Mark A. Tomai, John P. Vasilakos
      Pages 205-228
  4. Pre-clinical Vaccine Testing

    1. Front Matter
      Pages 249-249
    2. Tadele G. Kiros, Benoît Levast, Gaël Auray, Stacy Strom, Jill van Kessel, Volker Gerdts
      Pages 251-264
  5. Back Matter
    Pages 287-288

About this book


Prevention of infectious diseases by vaccination is one of the most significant achievements of modern medicine. During the 20th century, the average human life span in the developed world was about 70 years and it is expected to increase, with a significant portion of this increase directly attributed to vaccination.

Since the first empiric vaccination trials, knowledge and technology have enormously evolved and new vaccination strategies are emerging on the market. Indeed, in spite of the great success, conventional vaccination strategies sometimes may be ineffective and, above all, may raise safety concerns.

The aim of this book is to provide an overview of some of the technology platforms that have been realized or are currently under development to try to address unsolved and new issues in the field of vaccine development. The common denominator of all thematic areas described herein is the multidisciplinary teamwork. Most of the enabling technologies have been established by putting in the “melting pot”, expertise in fields that at first glance, may appear very far apart. I hope that this collection of articles will make the readers aware that vaccinology is rapidly taking a new direction and ceasing to be an empirical science. 


Biotechnology Immunology

Editors and affiliations

  • Selene Baschieri
    • 1
  1. 1.Italian National Agency for New Technolo, Energy and Sustainable Economic DevelopmENEARomeItaly

Bibliographic information