Atlas of Interstitial Cells of Cajal in the Gastrointestinal Tract

  • Terumasa┬áKomuro

Table of contents

  1. Front Matter
    Pages 1-1
  2. Distribution and Arrangement of ICC in the GI Tract

    1. Front Matter
      Pages 17-17
    2. Terumasa Komuro
      Pages 1-16
    3. Terumasa Komuro
      Pages 19-30
    4. Terumasa Komuro
      Pages 31-51
    5. Terumasa Komuro
      Pages 53-62
    6. Terumasa Komuro
      Pages 63-76
    7. Terumasa Komuro
      Pages 77-80
    8. Terumasa Komuro
      Pages 81-83
    9. Terumasa Komuro
      Pages 85-91
  3. Ultrastructural Demonstration of ICC and Allied Cells

    1. Front Matter
      Pages 93-93
    2. Terumasa Komuro
      Pages 95-112
    3. Terumasa Komuro
      Pages 125-128
  4. Back Matter
    Pages 95-95

About this book


This atlas will illustrate the distribution and morphological features of interstitial cells of Cajal (ICC) which are the key cells to understanding of the regulatory mechanism of gastrointestinal motility, since ICC act as both pacemaker and as intermediates in neural transmission, and since ICC show specific distribution patterns depending on their anatomical positions. All subtypes of ICC located in the different tissue layers and different levels of the gastrointestinal tract will be revealed by immunohistochemistry for Kit receptors and nerves by using mainly whole-mount stretch preparation of the guinea-pig tissues. Three-dimensional reconstruction of confocal images will particularly help the readers to understand the peculiar arrangement of ICC networks in situ and the correlation between ICC and nerves. Electron micrographs will help illustrate the characteristic features of ICC and their ultrastructural differences from fibroblasts, smooth muscles and other interstitial cells.


GI Tract ICC Morphology Smooth musculature c-kit

Authors and affiliations

  • Terumasa┬áKomuro
    • 1
  1. 1., Faculty of Human SciencesWaseda UniversityTokorozawaJapan

Bibliographic information