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© 2012

Systems Biology in Biotech & Pharma

A Changing Paradigm

Book

Part of the SpringerBriefs in Pharmaceutical Science & Drug Development book series (BRIEFSPSDD, volume 2)

Table of contents

About this book

Introduction

Systems Biology (SB) is a suite of technologies and methodologies that resulted, conceptually from the merging of two basic paradigms, reductionism and holism. It represents a combination of reductionist and holistic approaches to the relationships among the elements of a system, with the goal of identifying its emergent properties and defining, quantitatively, molecular, cellular, tissue, organ and whole body processes. One manifestation of SB is as a tool for hypothesis generation about a system that is typically too large and complex to understand by simple reasoning.

Keywords

Biochemical Networks Computational Systems Biology Drug Development Drug Discovery Systems Biology

Authors and affiliations

  1. 1., Chemical and Biological EngineeringVanderbilt UniversityNashvilleUSA
  2. 2.Genomic Health IncRedwoodUSA

Bibliographic information