Systems Biology in Biotech & Pharma

A Changing Paradigm

  • Aleš Prokop
  • Seth Michelson
Part of the SpringerBriefs in Pharmaceutical Science & Drug Development book series (BRIEFSPSDD, volume 2)

Table of contents

About this book

Introduction

Systems Biology (SB) is a suite of technologies and methodologies that resulted, conceptually from the merging of two basic paradigms, reductionism and holism. It represents a combination of reductionist and holistic approaches to the relationships among the elements of a system, with the goal of identifying its emergent properties and defining, quantitatively, molecular, cellular, tissue, organ and whole body processes. One manifestation of SB is as a tool for hypothesis generation about a system that is typically too large and complex to understand by simple reasoning.

Keywords

Biochemical Networks Computational Systems Biology Drug Development Drug Discovery Systems Biology

Authors and affiliations

  • Aleš Prokop
    • 1
  • Seth Michelson
    • 2
  1. 1., Chemical and Biological EngineeringVanderbilt UniversityNashvilleUSA
  2. 2.Genomic Health IncRedwoodUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-007-2849-3
  • Copyright Information The Author(s) 2012
  • Publisher Name Springer, Dordrecht
  • eBook Packages Medicine
  • Print ISBN 978-94-007-2848-6
  • Online ISBN 978-94-007-2849-3
  • Series Print ISSN 1864-8118
  • Series Online ISSN 1864-8126
  • About this book