The Biology of Subcellular Nitric Oxide

  • Tamás Rőszer

Table of contents

  1. Front Matter
    Pages 1-1
  2. General Concepts

    1. Front Matter
      Pages 1-1
    2. Tamás Rőszer
      Pages 3-16
  3. Nitric Oxide Synthesis in Prokaryote Cells

    1. Front Matter
      Pages 17-17
    2. Tamás Rőszer
      Pages 19-46
  4. Nitric Oxide in Plant Organelles

    1. Front Matter
      Pages 47-47
    2. Tamás Rőszer
      Pages 49-66
  5. At the Edge of the Plant and Animal Kingdom

    1. Front Matter
      Pages 81-81
  6. Nitric Oxide Synthesis in Animal Cells

    1. Front Matter
      Pages 103-103
    2. Tamás Rőszer
      Pages 105-132
    3. Tamás Rőszer
      Pages 133-144
    4. Tamás Rőszer
      Pages 145-155
    5. Tamás Rőszer
      Pages 157-167
    6. Tamás Rőszer
      Pages 179-185
    7. Tamás Rőszer
      Pages 187-200
  7. Back Matter
    Pages 194-194

About this book


This book fills in a gap in the NO literature. Recent progress in the field of NO-biology shows that NO is generated within distinct cell compartments, including specific plasma membrane regions, mitochondria, chloroplasts, peroxisomes, the Golgi-complex and intracellular membrane systems. NO synthesis plays specific roles in these compartments and, in turn, cell organelles also control intracellular NO levels. This monograph focuses on the roles played by the subcellular NO-signaling microdomains in the prokaryote-, fungus-, plant- and animal cells and shows how NO behaves as an intracellular signal in distinct cellular environments. This monograph also provides a summary of our knowledge on how NO synthesis came through evolution to be associated with organelles and subcellular compartments. Promotes the novel ideas that some functions of NO and its associations with subcellular units have been conserved during the evolution of the cell. A special chapter is dedicated to the biomedical relevance of subcellular NO synthesis, and this chapter also discusses the evidence that altered compartmentalization of NO-producing enzymes causes disease.


cell biology cell organelles free radical biology nitric oxide signal transmission

Authors and affiliations

  • Tamás Rőszer
    • 1
  1. 1.Cardiovascular Research CenterSpanish NationalMadridSpain

Bibliographic information