© 2011

Tumors of the Central Nervous System, Volume 1

Gliomas: Glioblastoma (Part 1)

  • M. A. Hayat

Part of the Tumors of the Central Nervous System book series (TCNS, volume 1)

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. M.A. Hayat
      Pages 3-8
    3. Kikuya Kato
      Pages 9-19
  3. Biomarkers and Diagnosis

    1. Front Matter
      Pages 21-21
    2. Nicole Simonavicius, Clare M. Isacke, Ivo J. Huijbers
      Pages 23-29
    3. Kyrre E. Emblem, Atle Bjornerud
      Pages 31-43
    4. Elizandra Braganhol, Andressa Bernardi, Angélica R. Cappellari, Márcia R. Wink, Ana M.O. Battastini
      Pages 45-51
    5. Luis F. Callado, Jesús M. Garibi, J. Javier Meana
      Pages 53-59
    6. Ming-Tao Yang, Tur-Fu Huang, Wen-Mei Fu
      Pages 61-66
    7. Eftychia Z. Kapsalaki, Ioannis Tsougos, Kyriaki Theodorou, Kostas N. Fountas
      Pages 67-79
    8. Marta M. Alonso, Juan Fueyo, Candelaria Gomez-Manzano
      Pages 89-97
    9. Randy L. Jensen, Rati Chkheidze
      Pages 99-108
    10. Marie E. Beckner, Mary L. Nordberg
      Pages 119-130
    11. Izabela Zawlik, Dorota Jesionek-Kupnicka, Pawel P. Liberski
      Pages 131-136
    12. Yasuo Sugita
      Pages 137-146
    13. Sabrina Facchino, Mohamed Abdouh, Gilbert Bernier
      Pages 159-166

About this book


The most recent developments in diagnostic and therapeutic aspects of Gliomas (Glioblastoma) in the brain are presented. The importance of personalized medicine and clinical validation for targeted therapy are discussed. The identification of various types of biomarkers is included. The identification and validation of brain cancer (glioblastoma) genes are discussed. Role of cancer stem cells in the initiation, progression, and persistence of malignant gliomas is explained. The use of surgical resection, chemotherapy (e.g., temozolomide), immunotherapy, and radiotherapy for malignant glioblastoma are pointed out. Standard (established) as well as newer imaging modalities (proton magnetic resonance spectroscopy) are discussed.


Chemotherapy Diagnosis Glioblastoma Radiotherapy Surgical Resection

Editors and affiliations

  • M. A. Hayat
    • 1
  1. 1.Dept. Biological SciencesKean UniversityUnionUSA

Bibliographic information

  • Book Title Tumors of the Central Nervous System, Volume 1
  • Book Subtitle Gliomas: Glioblastoma (Part 1)
  • Editors M. A. Hayat
  • Series Title Tumors of the Central Nervous System
  • DOI
  • Copyright Information Springer Science+Business Media B.V. 2011
  • Publisher Name Springer, Dordrecht
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-94-007-0343-8
  • Softcover ISBN 978-94-007-3558-3
  • eBook ISBN 978-94-007-0344-5
  • Edition Number 1
  • Number of Pages XXII, 434
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Cancer Research
  • Buy this book on publisher's site


From the reviews:

“This is an outstanding book on every molecular mediator of cancer stem cells, angiogenesis, surface markers, and CAD mediators of oncogenesis in the brain. … This is a very good book for neuropathologists and neurosurgeons.” (Joseph J. Grenier,, June, 2014)