Brain Protection in Schizophrenia, Mood and Cognitive Disorders

  • Michael S. Ritsner

Table of contents

  1. Front Matter
    Pages i-xv
  2. Neuroprotective Strategies and Mechanisms

    1. Front Matter
      Pages 1-1
    2. Hans-Gert Bernstein, Theresia S. Ernst, Uwe Lendeckel, Henrik Dobrowolny, Johann Steiner, Bernhard Bogerts
      Pages 45-66
    3. Wenming Li, Hongjun Fu, Moussa B.H. Youdim, Yuanping Pang, Yifan Han
      Pages 165-183
    4. Darcy Litteljohn, Emily Mangano, Shawn Hayley
      Pages 185-241
    5. Roberto Rodrigues, David J. Bonda, George Perry, Rudy J. Castellani, Gemma Casadesus, Hyoung-gon Lee et al.
      Pages 305-323
    6. William Lee, Vladimir Parpura
      Pages 325-340
  3. Part II. Neuroprotective Treatment and Neuromodulation

    1. Front Matter
      Pages 341-341
    2. Hannelore Ehrenreich, Claudia Bartels, Henning Krampe, Martin Begemann
      Pages 397-415
    3. Giacomo Salvadore, Rodrigo Machado-Vieira, Husseini K. Manji
      Pages 417-449
    4. Chris B. Aiken
      Pages 451-483
    5. Chanoch Miodownik, Vladimir Lerner
      Pages 505-553
    6. Raz Levin, Shany Edelman, Idan Shalev, Richard P. Ebstein, Uriel Heresco-Levy
      Pages 611-635
  4. Back Matter
    Pages 659-663

About this book


Neuroprotection is a novel perspective for the treatment of disorders that lead to neurodegeneration and disabilities as a result of deterioration of neurons due to apoptosis, oxidative stress, excitotoxicity, and other mechanisms. These mechanisms have implications not only for neurodegenerative disorders, but also for schizophrenia, mood and cognitive disorders. The purpose of this book is to provide an up-to-date overview of basic and clinical studies concerning the neuroprotective approach, mechanisms, and several compounds with neuroprotective properties that may contribute to more efficacious treatment of major mental health disorders. The book is divided into two sections. The first section serves as an introduction and overview of conceptual issues of the neuroprotective approach, and some neurobiological advances. Chapters in this section review definitions, perspectives, and issues that provide a conceptual base for the rest of the book. In addition, this part includes chapters in which the authors present and discuss the findings from basic studies of neurodegenerative mechanisms that are associated with the pathogenesis of major mental health disorders. The second section focuses on findings obtained from clinical trials with neuroprotective compounds, and neuromodulatory techniques. The take-home message is that principles of the neuroprotective approach may be applied to treatment of schizophrenia, mood and cognitive disorders. Contributors to this book are among the most active investigators and clinicians in the field who provide new perspectives not only clarifying ongoing controversies but also propose diverse aspects and new insights to neuroprotection. This book is intended for a broad readership, which includes a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, graduate students, and policy makers in the fields of mental health.


Cognitive disorders Depression Mood disorders Neuroprotection Neuroscience Schizophrenia neurons

Editors and affiliations

  • Michael S. Ritsner
    • 1
  1. 1.Sha'ar Menashe Mental Health CenterHaderaIsrael

Bibliographic information