The Future of Aging

Pathways to Human Life Extension

  • Gregory M. Fahy
  • Michael D. West
  • L. Stephen Coles
  • Steven B. Harris

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Introduction and Orientation

  3. The Future of Aging

    1. Front Matter
      Pages 225-225
    2. Christopher B. Heward
      Pages 227-278
    3. Roger Yu, Kaveh Navab, Mohamad Navab
      Pages 279-306
    4. Francisco J. Alcaín, Robin K. Minor, José M. Villalba, Rafael de Cabo
      Pages 331-356
    5. Michael R. Rose, Anthony D. Long, Laurence D. Mueller, Cristina L. Rizza, Kennedy C. Matsagas, Lee F. Greer et al.
      Pages 357-366
    6. Richard Aspinall, Wayne A. Mitchell
      Pages 489-520
    7. Rafal Smigrodzki, Francisco R. Portell
      Pages 521-541
    8. Abraham Aviv, John D. Bogden
      Pages 573-586
    9. John D. Furber
      Pages 587-621
    10. Robert J. Shmookler Reis, Joan E. McEwen
      Pages 623-639
    11. Clifford J. Steer, Betsy T. Kren
      Pages 641-666
    12. Aubrey D. N. J. de Grey
      Pages 667-684
  4. Back Matter
    Pages 807-866

About this book


Just as the health costs of aging threaten to bankrupt developed countries, this book makes the scientific case that a biological "bailout" could be on the way, and that human aging can be different in the future than it is today. Here 40 authors argue how our improving understanding of the biology of aging and selected technologies should enable the successful use of many different and complementary methods for ameliorating aging, and why such interventions are appropriate based on our current historical, anthropological, philosophical, ethical, evolutionary, and biological context. Challenging concepts are presented together with in-depth reviews and paradigm-breaking proposals that collectively illustrate the potential for changing aging as never before. The proposals extend from today to a future many decades from now in which the control of aging may become effectively complete. Examples include sirtuin-modulating pills, new concepts for attacking cardiovascular disease and cancer, mitochondrial rejuvenation, stem cell therapies and regeneration, tissue reconstruction, telomere maintenance, prevention of immunosenescence, extracellular rejuvenation, artificial DNA repair, and full deployment of nanotechnology. The Future of Aging will make you think about aging differently and is a challenge to all of us to open our eyes to the future therapeutic potential of biogerontology.


Anti-Aging Embryo aging biochemistry bioengineering cancer chemistry development morbidity regenerative medicine senescence

Editors and affiliations

  • Gregory M. Fahy
    • 1
  • Michael D. West
    • 2
  • L. Stephen Coles
    • 3
  • Steven B. Harris
    • 4
  1. 1.Intervene Biomedical, LLCNorcoUSA
  2. 2.BioTime, Inc.AlamedaUSA
  3. 3.Institute of Molecular Biology Department of Chemistry and Biochemistry Young HallUniversity of CaliforniaLos AngelesUSA
  4. 4.Critical Care Research, Inc.Rancho CucamongaUSA

Bibliographic information