Book 2010

The Future of Aging

Pathways to Human Life Extension

ISBN: 978-90-481-3998-9 (Print) 978-90-481-3999-6 (Online)

Table of contents (23 chapters)

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  1. Front Matter

    Pages i-xvii

  2. Introduction and Orientation

    1. Front Matter

      Pages 1-1

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      Chapter

      Pages 3-22

      Bridges to Life

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      Chapter

      Pages 23-38

      Analyzing Predictions: An Anthropological View of Anti-Aging Futures

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      Chapter

      Pages 39-61

      Towards Naturalistic Transcendence: The Value of Life and Life Extension to Persons as Conative Processes

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      Chapter

      Pages 63-86

      The Ethical Basis for Using Human Embryonic Stem Cells in the Treatment of Aging

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      Chapter

      Pages 87-126

      Evolutionary Origins of Aging

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      Chapter

      Pages 127-223

      Precedents for the Biological Control of Aging: Experimental Postponement, Prevention, and Reversal of Aging Processes

  3. The Future of Aging

    1. Front Matter

      Pages 225-225

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      Chapter

      Pages 227-278

      An Approach to Extending Human Lifespan Today

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      Chapter

      Pages 279-306

      Near Term Prospects for Ameliorating Cardiovascular Aging

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      Chapter

      Pages 307-329

      Near Term Prospects for Broad Spectrum Amelioration of Cancer

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      Chapter

      Pages 331-356

      Small Molecule Modulators of Sirtuin Activity

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      Chapter

      Pages 357-366

      Evolutionary Nutrigenomics

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      Chapter

      Pages 367-438

      Biological Effects of Calorie Restriction: Implications for Modification of Human Aging

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      Chapter

      Pages 439-449

      Calibrating Notch/TGF-β Signaling for Youthful, Healthy Tissue Maintenance and Repair

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      Chapter

      Pages 451-487

      Embryonic Stem Cells: Prospects of Regenerative Medicine for the Treatment of Human Aging

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      Chapter

      Pages 489-520

      Maintenance and Restoration of Immune System Function

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      Chapter

      Pages 521-541

      Mitochondrial Manipulation as a Treatment for Aging

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      Chapter

      Pages 543-571

      Life Extension by Tissue and Organ Replacement

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      Chapter

      Pages 573-586

      Telomeres and the Arithmetic of Human Longevity

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      Chapter

      Pages 587-621

      Repairing Extracellular Aging and Glycation

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      Chapter

      Pages 623-639

      Methuselah’s DNA: Defining Genes That Can Extend Longevity

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