The calcitonin gene-related peptide family

form, function and future perspectives

  • Deborah L. Hay
  • Ian M. Dickerson

Table of contents

  1. Front Matter
    Pages i-viii
  2. Yoshio Takei, Maho Ogoshi, Marty K. S. Wong, Shigenori Nobata
    Pages 1-21
  3. James Barwell, John Simms, Alex Conner, Debbie Hay, Mark Wheatley, David Poyner
    Pages 23-40
  4. Rasmus Just, John Simms, Sebastian G. B. Furness, Arthur Christopoulos, Patrick M. Sexton
    Pages 41-57
  5. Mahita Kadmiel, Kathleen M. Caron
    Pages 87-95
  6. Ki-Youb Park, Andrew F. Russo
    Pages 97-114
  7. Chia Lin Chang, Sheau Yu Teddy Hsu
    Pages 131-149
  8. Weiya Ma, Jean-Guy Chabot, Ara Schorscher-Petcu, Yinguo Hong, Zhiyong Wang, Remi Quirion
    Pages 151-171
  9. Thomas A. Lutz
    Pages 173-184
  10. Christopher A. Salvatore, Stefanie A. Kane
    Pages 185-197
  11. P.J. Wookey, A. Zulli, C. Lo, D. L. Hare, A. P. Schwarer, I. A. Darby et al.
    Pages 199-233
  12. Debbie L. Hay
    Pages 235-236

About this book


This book contains a comprehensive series of reviews on the calcitonin gene-related peptide (CGRP) family of peptides. This family of peptide hormones has a diverse and constantly expanding range of important physiologic functions, including regulation of blood calcium, vascular tension, feeding behavior and pain recognition.

This volume includes chapters on:

  • The adrenomedullin peptides and signalling
  • Ligand binding and activation of the CGRP receptor
  • Understanding amylin receptors
  • The CGRP-receptor component protein
  • The calcitonin peptide family
  • Genetic regulation of CGRP
  • Vascular actions of CGRP and adrenomedullin
  • Intermedin/adrenomedullin 2 function
  • CGRP and adrenomedullin as pain-related peptides
  • Amylinergic control of ingestive behaviour
  • Calcitonin receptors

This book discusses their receptors, physiological and pathophysiological functions and potential as clinical targets. It will appeal to researchers who study any of these peptides and those with an interest in migraine therapy due to the involvement of CGRP in this disorder. The book is unique because it brings together research on the whole peptide family for the first time in several years. It will be a useful reference volume for researchers in this area. This book will also appeal to researchers in the broader field of bioactive peptides.


genes hormone hormones inflammation pain peptides protein

Editors and affiliations

  • Deborah L. Hay
    • 1
  • Ian M. Dickerson
    • 2
  1. 1.School of Biological SciencesUniversity of AucklandAuckland New Zealand
  2. 2.University of AucklandAucklandNew Zealand

Bibliographic information