Sepsis and Organ Dysfunction

The Challenge Continues

  • A. E. Baue
  • G. Berlot
  • A. Gullo
  • J.-L. Vincent
Conference proceedings

Table of contents

  1. Front Matter
    Pages I-IX
  2. Introduction

    1. A. E. Baue
      Pages 11-15
  3. Sepsis and Organ Dysfunction. The Challenge Continues

    1. G. Berlot, U. Lucangelo, A. Gullo
      Pages 17-33
  4. Oxygen Transport in Sepsis

    1. Front Matter
      Pages 35-35
    2. A. Mayr, W. Pajk, W. Hasibeder
      Pages 43-48
    3. C. Adembri, A. R. De Gaudio, G. P. Novelli
      Pages 49-56
    4. W. Pajk, H. Knotzer, W. Hasibeder
      Pages 57-63
  5. Organ Dysfunction and Biohumoral Mismatch in Sepsis

    1. Front Matter
      Pages 65-65
    2. J. F. Pálizas
      Pages 67-76
    3. N. Latronico, G. F. Bussi, A. Candiani
      Pages 77-83
    4. J. A. Kellum
      Pages 91-101
    5. H. Zhang, C. Hsia, G. Porro
      Pages 107-112
  6. Sepsis Trial

    1. Front Matter
      Pages 113-113
    2. J.-L. Vincent
      Pages 115-121
    3. M. Meisner, K. Reinhart
      Pages 137-143
  7. Back Matter
    Pages 175-178

About these proceedings


An experienced physician knows how to recognize a patient suffering from sepsis, but cannot accurately determine whether the patient will survive. Cardinal elements of the treatment for sepsis include specific antibiotic and vasoactive drugs, enteral and parenteral nutrition, artificial respiration, and optimization of the oxygen transport to tissues. Nonetheless, with a certain frequency, these techniques are insufficient to ensure the recovery of a critically ill patient, especially when it is necessary to overcome functional alterations subsequent to organ and vital-system overload. The key elements in the progression of the sepsis-MODS syndrome are tied to numerous factors. These include: the severity and location of the lesion; the patient's age; the remaining functional reserve; the presence of mediatory which may be stimulatory, inhibitory or both.


Sepsis epidemiology pathophysiology respiration shock

Editors and affiliations

  • A. E. Baue
    • 1
  • G. Berlot
    • 2
  • A. Gullo
    • 2
  • J.-L. Vincent
    • 3
  1. 1.Department of Surgery, Health Sciences CenterSaint Louis UniversitySt. LouisUSA
  2. 2.Department of Anaesthesia, Intensive Care and Pain Therapy, Cattinara HospitalUniversity of TriesteTriesteItaly
  3. 3.Department of Intensive Care, Erasme University HospitalFree University of BrusselsBelgium

Bibliographic information