New Frontiers of MR-based Techniques in Multiple Sclerosis

  • Massimo Filippi
  • Giancarlo Comi

Part of the Topics in Neuroscience book series (TOPNEURO)

Table of contents

  1. Front Matter
    Pages I-X
  2. M. Filippi, M. Rovaris, G. Comi
    Pages 1-3
  3. M. Rovaris, M. Filippi
    Pages 11-32
  4. M. Filippi, M. A. Rocca
    Pages 33-45
  5. O. Gonen, R. I. Grossman
    Pages 47-71
  6. W. Rashid, D. H. Miller
    Pages 73-82
  7. M. Filippi, M. A. Rocca
    Pages 83-97
  8. A. Kangarlu, K. W. Rammohan, E. C. Bourekas, D. W. Chakeres
    Pages 99-104
  9. Back Matter
    Pages 105-107

About this book


In the past few years there have been impressive advances in the implementation of modern MRI techniques for the assessment of MS patients with the ultimate goal to define MRI markers of MS evolution. The authors of this volume not only review these new techniques, such as magnetization transfer (MT) MRI, diffusion-weighted (DW) MRI and proton MR spectroscopy (MRS), that are increasingly being used to monitor MS evolution, but also those, such as functional MRI (fMRI), cell-specific MRI, perfusion MRI, and microscopic imaging with ultra-high field MRI, that are emerging as additional promising tools for improving our understanding of MS pathophysiology. Strengths and weaknesses of all these modern quantitative MRI techniques for the study of MS are extensively covered in this book. The book also provides a valuable summary of the state of the art.


MRI Nervous System Proton magnetic resonance spectroscopy diffusion-weighted MRI magnetization transfer MRI multiple sclerosis

Editors and affiliations

  • Massimo Filippi
    • 1
  • Giancarlo Comi
    • 2
  1. 1.Neuroimaging Research Unit, Department of NeuroscienceScientific Institute and UniversityOspedale San Raffaele, MilanItaly
  2. 2.Department of NeurologyScientific Institute and UniversityOspedale San Raffaele, MilanItaly

Bibliographic information