Multiple Primary Malignancies

  • Andrea Renda

Part of the Updates in Surgery book series (UPDATESSURG)

Table of contents

  1. Front Matter
    Pages I-XXII
  2. Andrea Renda, Nicola Carlomagno
    Pages 1-6
  3. Maurizio Montella, Carlotta Buzzoni, Anna Crispo
    Pages 7-26
  4. Nicola Carlomagno, Francesca Duraturo, Gennaro Rizzo, Cristiano Cremone, Paola Izzo, Andrea Renda
    Pages 51-61
  5. Pietro Lombari, Loredana Vecchione, Antonio Farella, Sebastiano Grassia, Fernando De Vita, Giuseppe Catalano et al.
    Pages 63-81
  6. Michele Santangelo, Sergio Spiezia, Marco Clemente, Andrea Renda, Arturo Genovese, Giuseppe Spadaro et al.
    Pages 83-96
  7. Stefania Staibano, Massimo Mascolo, Lorenzo Lo Muzio, Gennaro Ilardi, Loredana Nugnes, Concetta Dodaro et al.
    Pages 97-105
  8. Nicola Carlomagno, Luigi Pelosio, Akbar Jamshidi, Marius Yabi, Francesca Duraturo, Paola Izzo et al.
    Pages 107-128
  9. Carlo de Werra, Ivana Donzelli, Mario Perone, Rosa Di Micco, Gianclaudio Orabona
    Pages 129-142
  10. Matilde Pensabene, Rosaria Gesuita, Ida Capuano, Caterina Condello, Ilaria Spagnoletti, Eleonora De Maio et al.
    Pages 143-155
  11. Concetta Dodaro, Enrico Russo, Giuseppe Spinosa, Luigi Ricciardelli, Andrea Renda
    Pages 179-194
  12. Alessandro Scotti, Alessandro Borrelli, Gioacchino Tedesco, Francesca Di Capua, Cristiano Cremone, Michele Giuseppe Iovino et al.
    Pages 195-210
  13. Marcello Caggiano, Angela Mariano, Massimiliano Zuccaro, Sergio Spiezia, Marco Clemente, Vincenzo Macchia
    Pages 211-220
  14. Giuseppe Galloro, Luca Magno, Giorgio Diamantis, Antonio Pastore, Simona Ruggiero, Salvatore Gargiulo et al.
    Pages 221-230
  15. Vincenzo Tammaro, Sergio Spiezia, Salvatore D’Angelo, Simone Maurea, Giovanna Ciolli, Marco Salvatore
    Pages 231-244
  16. Nicola Carlomagno, Luigi Pelosio, Akbar Jamshidi, Francesca Duraturo, Paola Izzo, Andrea Renda
    Pages 245-266
  17. Pietro Lombari, Gaetano Aurilio, Fernando De Vita, Giuseppe Catalano
    Pages 267-279
  18. Andrea Renda
    Pages 281-284
  19. Back Matter
    Pages 285-287

About this book


Two to three decades ago, multiple primary malignancies (MPM) were considered to be simply a clinical curiosity, with sporadic reports, mostly single case descriptions, found in the literature. While in the last few years, analyses of larger series have been published, the number of cases has still been relatively small and most of the reports have addressed a single type of primary tumor and its associations.

With the improved prognosis and survival of cancer patients, MPM is becoming increasingly prevalent in this population, necessitating a better understanding of the characteristics and associations of the malignancies involved. Thus, as a prerequisite, a universal definition and an internationally accepted classification system, based on chronological, pathological, clinical, and other parameters, are needed. Moreover, much remains to be learned about the etiology of MPM, whether genetic, iatrogenic, or environmental.

Several of the hereditary syndromes, such as familial adenomatous polyposis, hereditary non-polyposis colorectal cancer, hereditary breast-ovarian cancer, and multiple endocrine neoplasia, are already well-known and their characteristics in relation to MPM must be kept in mind. Nonetheless, along with these syndromes, there are sporadic and apparently casual associations between primary neoplasms that can involve almost any part of the body.

This volume points out the clinical aspects of MPM and discusses the diagnostic and therapeutic problems that are encountered in treating these patients. "DNA-guided" surgery, currently confined to the treatment of patients with hereditary syndromes, will, along with other novel treatment strategies, no doubt play an increasingly greater role in the therapy of MPM.

This work presents state-of-the-art information about MPM that is aimed at a broad range of medical specialists, including surgeons, endoscopists, oncologists, and geneticists,. The goal is to improve our understanding of this group of diseases as well the treatment of these patients.


Tumour classification endoscopy epidemiology genetic imaging imaging techniques surgery therapy

Authors and affiliations

  • Andrea Renda
    • 1
  1. 1.Surgical, Anesthesiology-rianimative and Emergency Sciences DepartmentFederico II UniversityNaplesItaly

Bibliographic information

  • DOI
  • Copyright Information Springer Milan 2009
  • Publisher Name Springer, Milano
  • eBook Packages Medicine
  • Print ISBN 978-88-470-1094-9
  • Online ISBN 978-88-470-1095-6
  • Buy this book on publisher's site