Hand Transplantation

  • Marco Lanzetta
  • Jean-Michel Dubernard
  • Palmina Petruzzo

Table of contents

  1. Front Matter
    Pages I-XXI
  2. Historical Remarks

    1. Front Matter
      Pages 1-1
    2. Bruce W. Conolly, Mario Benanzio
      Pages 3-10
  3. Experimental Limb Transplantation

    1. Front Matter
      Pages 25-25
    2. Takako Kanatani, Marco Lanzetta, G. Alex Bishop
      Pages 41-46
    3. Keiichi Muramatsu, Kazuteru Doi, Hiroshi Tanaka, Toshihiko Taguchi
      Pages 47-56
    4. Marco Lanzetta, Alexander Kubitskiy, G. Alex Bishop, Jian Li, Geoffrey W. McCaughan
      Pages 57-59
    5. Maria Siemionow, Yalcin Kulahci
      Pages 61-77
    6. Rollin K. Daniel, Kevin A. Brenner
      Pages 89-94
    7. Steven E. R. Hovius, H. Mischa Zuijdendorp, Jeroen J. P. D. Stevens
      Pages 95-104
  4. Ethics and Medico-Legal Implications

  5. Organization of Hand Transplantation

  6. Surgical Technique of Hand Transplantation

    1. Front Matter
      Pages 171-171
    2. Giovanna Lucchini, Francesca Magni, Marco Lanzetta
      Pages 173-178
    3. Giovanni Vitale, Ettore Martinez, Paolo Maisano, Maurizio Saini, Lorenzo De Marchi, Giacomo Bellani
      Pages 179-185
    4. Marco Lanzetta, Roberta Nolli, Lorenzo Bettella
      Pages 187-189
    5. Aram Gazarian
      Pages 191-196
  7. Immunology of Hand Transplantation

    1. Front Matter
      Pages 207-207
    2. Olivier Thaunat, Emmanuel Morelon
      Pages 209-214
  8. Immunosuppressive Therapy

    1. Front Matter
      Pages 215-215
    2. Palmina Petruzzo
      Pages 217-221
    3. Lionel Badet, Palmina Petruzzo, Nicole Lefrançois, Emmanuel Morelon, Xavier Martin, Jean-Michel Dubernard
      Pages 223-226
    4. Stefan Schneeberger, Raimund Margreiter, Stefano Lucchina, Marco Lanzetta, Hugo Bonatti
      Pages 227-235
    5. Giovanna Lucchini, Pietro Pioltelli, Marco Lanzetta
      Pages 237-240
    6. Daniele Veritti, Lanzetta Marco
      Pages 241-246
  9. Limb Rejection and Monitoring

    1. Front Matter
      Pages 247-247
    2. Palmina Petruzzo
      Pages 259-261
    3. Marco Lanzetta, Luca Rovati
      Pages 263-268
  10. Functional Recovery of Transplanted Hands

    1. Front Matter
      Pages 269-269
    2. Markus Gabl, Sigurd Pechlaner, Martin Lutz, Rohit Arora, Michael Blauth, Michael Rieger et al.
      Pages 271-277
    3. Graziella Urso, Luisa Stroppa, Tatiana Barchitta, Paola Cossa
      Pages 279-289
    4. Hélène Parmentier
      Pages 303-306

About this book


Transplanting a limb has been a dream of humanity – until 1998 when an international team of surgeons gathered in Lyon, France, and performed the first hand transplantation in history. Since then, groups in the United States, China, Austria, Italy and Belgium have launched hand transplantation programmes. In 2002, the International Registry on Hand and Composite Tissue Transplantation (IRHCTT) was created with the purpose of collecting and analysing data from every centre. This book presents the global experimental and clinical experience on hand transplantation and all types of other composite tissue allografts so far performed. A complete review of all aspects of these innovative and ground-breaking procedures is clearly presented in 15 different sections. They include the experimental basis of hand transplantation, strategies for selecting ideal candidates and preparing successful hand transplantation programmes, surgical techniques, most effective immunosuppressive drug regimes, analysis of the unique immunological behaviour of these transplants and rehabilitation protocols to achieve optimal sensory and motor recovery. Each section is dedicated to a special issue, such as psychological and medicolegal implications, brain remodelling after hand transplantation and introduction of a new scoring system for overall comprehensive outcome evaluation. A complete list of composite tissues allografts currently carried out around the world is reported in detail, including the face, abdominal wall, uterus, larynx and knee joint. This book is a milestone in the medical literature and represents a great asset for every scientific library.


Antigen Hand transplantation Rehabilitation and physiotherapy of skeletal disorders abdominal wall amputation clinical trial complication hand infection knee outcome physiotherapy rehabilitation surgical techniques transplantation

Editors and affiliations

  • Marco Lanzetta
    • 1
    • 2
    • 3
  • Jean-Michel Dubernard
    • 4
  • Palmina Petruzzo
    • 4
    • 5
  1. 1.Italian Institute of Hand SurgeryMonza,MilanItaly
  2. 2.University of CanberraAustralia
  3. 3.International Hand and CompositeTissue Allograft SocietyAustralia
  4. 4.Department of TransplantationÉdouard Herriot HospitalLyonFrance
  5. 5.Department of SurgeryUniversity of CagliariItaly

Bibliographic information