Moyamoya Disease Update

  • Byung-Kyu Cho
  • Teiji Tominaga

Table of contents

  1. Front Matter
    Pages i-xx
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Teiji Tominaga
      Pages 3-11
    3. Kent Doi, Ken-ichiro Kikuta
      Pages 12-22
    4. Chang-Wan Oh, Gyojun Hwang
      Pages 23-25
  3. Epidemiology

    1. Front Matter
      Pages 27-27
    2. Koichi Oki, Haruhiko Hoshino, Norihiro Suzuki
      Pages 29-34
    3. Joong-Uhn Choi
      Pages 35-37
  4. Genetics

    1. Front Matter
      Pages 39-39
    2. Shigeo Kure
      Pages 41-45
    3. Shigeo Kure
      Pages 46-50
    4. Hyun-Seung Kang, Kyu-Chang Wang
      Pages 51-53
    5. Myoung Hee Park, Seok Ho Hong, Kyu-Chang Wang
      Pages 54-59
  5. Pathophysiology I: Protein, Cell, and Immunology

    1. Front Matter
      Pages 61-61
    2. Seung-Ki Kim, Kyu-Chang Wang, Byung-Kyu Cho
      Pages 63-68
    3. Jin Hyun Kim, Seung-Ki Kim, Kyu-Chang Wang
      Pages 73-81
    4. Ji Hoon Phi, Seung-Ki Kim, Kyu-Chang Wang, Byung-Kyu Cho
      Pages 82-86
  6. Pathophysiology II: Hemodynamics, Biomechanical Aspect

    1. Front Matter
      Pages 87-87
    2. Jeong Chul Kim, Eun Bo Shim
      Pages 89-98
  7. Clinical Features

    1. Front Matter
      Pages 105-105
    2. Reizo Shirane, Miki Fujimura
      Pages 110-113
    3. Shigeru Nogawa, Norihiro Suzuki
      Pages 114-117
    4. Kentaro Hayashi, Izumi Nagata
      Pages 118-125
    5. Hae Il Cheong, Yong Choi
      Pages 126-131
    6. Miki Fujimura, Teiji Tominaga
      Pages 132-138
  8. Diagnostic Evaluation I: Morphological Imaging

    1. Front Matter
      Pages 139-139
    2. Kiyohiro Houkin, Satoshi Iihoshi, Takeshi Mikami
      Pages 141-149
    3. Takeshi Mikami, Satoshi Iihoshi, Kiyohiro Houkin
      Pages 150-157
    4. Kazuhiko Nishino, Takatoshi Sorimachi, Yukihiko Fujii
      Pages 158-167
  9. Diagnostic Evaluation II: Functional Imaging

    1. Front Matter
      Pages 169-169
    2. Jyoji Nakagawara
      Pages 171-180
    3. Jin Chul Paeng, Dong Soo Lee
      Pages 181-188
    4. Jyoji Nakagawara
      Pages 189-196
    5. Jung-Eun Cheon, In-One Kim
      Pages 197-204
  10. Diagnostic Evaluation III: Electrophysiology

    1. Front Matter
      Pages 213-213
    2. Jong-Hee Chae, Ki Joong Kim
      Pages 215-219
    3. Nobukazu Nakasato, Akitake Kanno, Teiji Tominaga
      Pages 220-224
  11. Surgical Technique

    1. Front Matter
      Pages 225-225
    2. Toshio Matsushima, Masatou Kawashima, Jun Masuoka
      Pages 227-233
    3. Chae-Yong Kim, Byong Cheol Kim
      Pages 241-247
    4. Dal-Soo Kim
      Pages 248-251
    5. O-Ki Kwon, Seong Hyun Kim
      Pages 252-260
  12. Surgical Outcome

    1. Front Matter
      Pages 261-261
    2. Byung-Kyu Cho, Seung-Ki Kim, Kyu-Chang Wang
      Pages 263-274
    3. Miki Fujimura, Teiji Tominaga
      Pages 275-280

About this book


Moyamoya disease (MMD) was first reported as a new entity among vascular disorders in 1957. Named for the abnormal vascular networks found around the occluded distal internal carotid artery, it is the most common pediatric cerebrovascular disease in East Asia. In recent years large amounts of data on MMD have been collected and important investigations have been carried out in Japan and Korea, even as the pathophysiology of the disease remains to be discovered. This monograph covers a diversity of topics and presents a systematic compilation of the data and current status of MMD in clinical practice and basic research. With contributions by more than 70 authors, the book includes sections on genetics, computational analysis of hemodynamic shear stress, new imaging techniques, and endovascular treatment of MMD, along with practical applications and future directions for gene and stem cell therapies. For neurosurgeons as well as neurologists and pediatricians, this volume will help lead to more efficient and informed management of MMD.


MMD Moyamoya Disease PET SPECT anesthesia cerebrovascular disease cognition electroencephalography (EEG) magnetic resonance imaging (MRI) muscle neurosurgery pathophysiology positron emission tomography (PET) surgery surgical technique

Editors and affiliations

  • Byung-Kyu Cho
    • 1
  • Teiji Tominaga
    • 2
  1. 1.Department of NeurosurgerySeoul National University College of Medicine Seoul National University Children's HospitalJongno-guRepublic of Korea
  2. 2.Department of NeurosurgeryTohoku University Graduate School of MedicineAoba-kuJapan

Bibliographic information