Neurochemical Monitoring in the Intensive Care Unit

Microdialysis, Jugular Venous Oximetry, and Near-Infrared Spectroscopy, Proceedings of the 1st International Symposium on Neurochemical Monitoring in the ICU held concurrently with the 5th Biannual Conference of the Japanese Study Group of Cerebral Venous Oximetry in Tokyo, Japan, May 20–21, 1994

  • Takashi Tsubokawa
  • Anthony Marmarou
  • Claudia Robertson
  • Graham Teasdale
Conference proceedings

Table of contents

  1. Front Matter
    Pages III-XIX
  2. Basic Problems of Microdialysis Technique

    1. Front Matter
      Pages 1-1
    2. Toshiki Shirotani, Katsuji Shima, Miwako Iwata, Hideyuki Kita, Hiroo Chigasaki
      Pages 34-41
    3. Makoto Furuichi, Shuhei Miyazaki, Yoichi Katayama, Takashi Tsubokawa
      Pages 42-46
  3. Clinical Application of Microdialysis Technique

    1. Front Matter
      Pages 57-57
    2. Lars Hillered, Lennart Persson
      Pages 59-63
    3. R. Bullock, A. Zauner, O. Tsuji, J. J. Woodward, A. T. Marmarou, H. F. Young
      Pages 64-71
    4. Tatsuro Kawamata, Yoichi Katayama, Kosaku Kinoshita, Takashi Tsubokawa
      Pages 72-77
    5. J. Clay Goodman, Daniel P. Robertson, Shankar P. Gopinath, Raj K. Narayan, Robert G. Grossman, Richard K. Simpson Jr. et al.
      Pages 78-83
  4. Clinical Impact of Jugular Bulb Oximetry

    1. Front Matter
      Pages 85-85
    2. Hiroyuki Yokota, Yasuhiro Yamamoto, Matoaki Nakabayashi, Akira Fuse, Kunihiro Mashiko, Hiroshi Henmi et al.
      Pages 98-104
    3. Hiroshi Inagawa, Yasusei Okada, Sou Suzuki, Kazuyuki Ono, Kazuhiko Maekawa
      Pages 112-119
    4. Motoaki Nakabayashi, Hiroyuki Yokota, Akira Fuse, Hidetaka Sato, Shigeki Kushimoto, Kazuyoshi Kato et al.
      Pages 120-126
    5. Toshiaki Ikeda, Kazumi Ikeda, Narihiro Yoshimatsu, Hideto Kaneko, Masatoshi Sugi, Tohru Iizuka et al.
      Pages 134-139
    6. Teruyasu Hirayama, Yoichi Katayama, Takashi Tsubokawa
      Pages 146-150
  5. Jugular Bulb Oximetry in Head Injured Patients

    1. Front Matter
      Pages 151-151
    2. Claudia S. Robertson
      Pages 153-159
    3. Yasufumi Mizutani, Tsuyoshi Katabami, Masahiko Udzura, Takeki Ogawa, Hiroaki Sekino, Yoshio Taguchi et al.
      Pages 172-179
  6. Characteristics of Near-Infrared Spectroscopy

    1. Front Matter
      Pages 191-191
    2. Valerie Pollard, Eric A. DeMelo, Donald J. Deyo, Rebecca Dalmeida, R. Widman, Donald S. Prough
      Pages 193-203
    3. A. Unterberg, A. Rosenthal, G. H. Schneider, K. Kiening, W. R. Lanksch
      Pages 204-210
    4. Hidehiko Kushi, Tadashi Shibuya, Motoaki Fujii, Yoichi Katayama, Takashi Tsubokawa
      Pages 211-217
    5. Issei Nara, Toshiyuki Shiogai, Nahoko Tanaka, Manabu Tokitsu, Isamu Saito
      Pages 218-225
  7. Back Matter
    Pages 235-240

About these proceedings


Neurophysiological recording is the major neuromonitoring technique employed in ICU. In addition, continuous recording of intracranial pressure has proved to provide infomation useful for critical care of the patient with severe brain damage. It is, however, difficult to assess neurochemical and/or metabolic environments of the brain with these conventional neuromoni­ toring techniques. Information regarding these changes, if available on a real-time basis, is undoubtedly useful for patient care. Many important developments in bedside techniques to monitor these changes have been achieved during the last few years. It was the consensus of the editors that a symposium to exchange knowledge concerning recent advances in such techniques would be valuable. With this background, the First International Symposium of Neuro­ chemical Monitoring in ICU held May 20-21, 1994, in Tokyo, Japan. It was not the intention of the organizers that this symposium should survey the whole field of neuromonitoring in ICU. The symposium was thus focused on clinical application of microdialysis, jugular venous oximetry, and near­ infrared spectroscopy, which currently appear to be the most promising techniques for monitoring neurochemical and metabolic changes in the brain in a clinical setting. We termed these techniques collectively as neuro­ chemical monitoring, contrasting them with neurophysiological monitoring in ICU. The concept that has motivated this symposium was to provide an opportunity to exchange up-to-date summaries on issues currently debated for these techniques. This volume is based on the papers presented at the symposium.


Brain trauma Critical care Juglar venous oximetry Microdialysis Near-infrared Spectroscopy clinical application

Editors and affiliations

  • Takashi Tsubokawa
    • 1
  • Anthony Marmarou
    • 2
  • Claudia Robertson
    • 3
  • Graham Teasdale
    • 4
  1. 1.Department of Neurological SurgeryNihon University School of MedicineTokyoJapan
  2. 2.Division of Neurosurgery, Medical College of VirginiaVirginia Commonwealth UniversityRichmondUSA
  3. 3.Department of NeurosurgeryBaylor College of MedicineHoustonUSA
  4. 4.Department of Neurosurgery, Southern General HospitalUniversity of GlasgowGlasgowScotland, UK

Bibliographic information