Strategic Medical Science Against Brain Attack

  • Haruhiko Kikuchi

Table of contents

  1. Front Matter
    Pages II-XIII
  2. Strategies using neuritic reconstruction and neuroregeneration

    1. Front Matter
      Pages 1-1
    2. Jun Takahashi, Hiroki Toda, Nobuo Hashimoto
      Pages 3-20
  3. Strategies of neuroprotection

    1. Front Matter
      Pages 29-29
    2. Shobu Namura, Alessandro Alessandrini
      Pages 31-44
    3. Yasushi Takagi, Itaro Hattori, Kazuhiko Nozaki, Nobuo Hashimoto, Junji Yodoi
      Pages 45-56
  4. Strategies using survival or death signals in neurons

    1. Front Matter
      Pages 95-95
    2. Hiroshi Kiyama, Sumiko Kiryu-Seo, Kazuhiko Namikawa
      Pages 115-124
  5. Strategies for and from cortical spreading depression

    1. Front Matter
      Pages 125-125
    2. Chiaki Yokota, Yuji Kuge, Masafumi Tagaya, Yasuhiro Hasegawa, Takeo Abumiya, Go Kito et al.
      Pages 127-144
    3. Hiroji Yanamoto, Jing-Hui Xue, Izumi Nagata, Nobuo Hashimoto, Masahiro Sakata, Ikuko Mizuta et al.
      Pages 145-167
  6. Strategies using hypothermia

    1. Front Matter
      Pages 169-169
    2. Hiroaki Naritomi, Kazuyuki Nagatsuka, Kotaro Miyashita, Hiroshi Oe, Hiroshi Moriwaki, Zhen He et al.
      Pages 171-185
    3. Nobuyuki Yasui, Shingo Kawamura, Akifumi Suzuki, Hiromu Hadeishi, Jun Hatazawa
      Pages 186-194
    4. Yasuji Yoshida, Octavio J. Arroyo, Carlos A. Arellanes, Nobuyuki Yasui
      Pages 195-201
    5. Hiroji Yanamoto, Izumi Nagata, Hideki Sakai, Yoichi Niitsu, Zhiwen Zhang, Jing-Hui Xue et al.
      Pages 202-220
  7. Strategies for cerebral aneurysm and vasospasm

    1. Front Matter
      Pages 221-221
    2. Masafumi Morimoto, Noriaki Kume, Susumu Miyamoto, Akira Mizoguchi, Kazuhiko Nozaki, Nobutake Sadamasa et al.
      Pages 223-233
    3. Taro Komuro, Soichi Miwa, Yoshifumi Kawanabe, Xiao-Feng Zhang, Tatsuya Sawamura, Manabu Fukumoto et al.
      Pages 254-265
  8. Developments in brain-imaging technology

    1. Front Matter
      Pages 267-267
    2. Chuzo Tanaka, Toshihiko Ebisu, Masahiro Umeda, Ichio Aoki, Masaki Fukunaga, Yasuharu Watanabe et al.
      Pages 269-292
  9. Back Matter
    Pages 293-294

About this book


The importance of the therapeutic time window for ischemic stroke has been widely accepted for a long time. Consequently, I have been thinking about the past, when the term "brain attack," which was reimported from the United States, began to spread by repetition. In the 1980s, I had made an enthusiastic study of acute-phase cerebral revascularization for ischemic stroke. At that time, we could cure only a quite lim­ ited number of patients, such as those who already were hospitalized or who, fortu­ nately, were brought to the hospital within a few hours from the onset of the stroke. RM Crowell, in his 1977 report! on cases of failure, had identified the consider­ able problems in acute-phase cerebral revascularization as diagnosis of tissue reversibility, brain-protective reagents or methods, and effective techniques for revascularization. I remember that we strongly endorsed his opinion. Recently, the basic study of stroke has advanced significantly, resulting in newly developed materials and new experimental techniques, which are introduced in this book. I hope that new basic knowledge will be clinically applied.


Brain protection Brain science Cerebrovascular diseases Neuro-regenesis Stroke aneurysm brain cerebral ischemia clinical application depression neurons neuroprotection

Editors and affiliations

  • Haruhiko Kikuchi
    • 1
  1. 1.National Cardio-Vascular CenterSuita, OsakaJapan

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