Viral Hepatitis and Liver Disease

Proceedings of the International Symposium on Viral Hepatitis and Liver Disease: Molecules Today, More Cures Tomorrow, Tokyo, May 10–14, 1993 (1993 ISVHLD)

  • K. Nishioka
  • H. Suzuki
  • S. Mishiro
  • T. Oda
Conference proceedings

Table of contents

  1. Front Matter
    Pages i-xxii
  2. Prologue

  3. Hepatitis Viruses A, B, C, D, and E

    1. Front Matter
      Pages 17-17
    2. Perspectives

      1. Robert H. Purcell
        Pages 19-21
      2. Michael Houghton, Q.-L. Choo, G. Kuo, R. Ralston, M. Selby, A. Weiner et al.
        Pages 33-37
      3. John L. Gerin, John L. Casey, Katherine F. Bergmann
        Pages 38-41
      4. Daniel W. Bradley, Michael A. Purdy
        Pages 42-45
    3. Taxonomy

      1. Joseph L. Melnick, Colin R. Howard
        Pages 47-49
      2. Stanley M. Lemon, Betty H. Robertson
        Pages 50-53
      3. E. C. Holmes, P. Simmonds, T.-A. Cha, S.-W. Chan, F. McOmish, B. Irvine et al.
        Pages 57-62
      4. John L. Gerin
        Pages 63-64
  4. New Hepatitis Viruses?

    1. Front Matter
      Pages 69-69
    2. Stephen M. Feinstone, Tatsuo Miyamura
      Pages 71-72
    3. Maria Buti, Rosendo Jardi, Francisco Rodriguez-Frias, Jose Quer, R. Esteban, Jaime Guardia
      Pages 77-79
    4. Nicolaos C. Tassopoulos, Angelos Hatzakis, Mary Kuhns, Vivi Miriagou, Ioanna Delladetsima, Maria G. Koutelou et al.
      Pages 80-84
    5. Patrick Marcellin, Michèle Martinot-Peignoux, Franck Gabriel, Michel Branger, Alida Elias, Claude Degott et al.
      Pages 85-86
    6. Michael O. Favorov, O. O. Znoiko, T. L. Yashina, P. Patel, E. Z. Goldberg, Y. E. Khudyakov et al.
      Pages 87-88
  5. Biology

    1. Front Matter
      Pages 89-89
    2. Kenichi Matsubara
      Pages 91-91
    3. Olivier Rosmorduc, Marie-Anne Petit, Francis Capel, Martin Weber, Christian Bréchot, Dina Kremsdorf
      Pages 92-96
    4. Hiroshi Yoshikura, Minako Hijikata, Yohko K. Shimizu
      Pages 101-103
    5. Gregor Meyers, Robert Stark, Norbert Tautz, Tillmann Rümenapf, Gabi Unger, Heinz-Jürgen Thiel
      Pages 106-110
    6. Ludmila V. S. Asher, W. Parlett, J. Egan, S. Polo, R. Baumgartner
      Pages 111-114
    7. Yohko K. Shimizu, Minako Hijikata, Aikichi Iwamoto, Robert H. Purcell, Hiroshi Yoshikura
      Pages 115-117
    8. Akio Nomoto, Kyoko Tsukiyama-Kohara, Michinori Kohara
      Pages 118-120
    9. Kyoko Tsukiyama-Kohara, Michinori Kohara, Akio Nomoto
      Pages 121-124
    10. H. Kettinen, K. Grace, S. Grunert, B. Clarke, D. Rowlands, R. Jackson
      Pages 125-131
    11. Arash Grakoui, David W. McCourt, Czeslaw Wychowski, Chao Lin, Stephen M. Feinstone, Charles M. Rice
      Pages 136-139
    12. Makoto Hijikata, Hiroto Mizushima, Yasunori Tanji, Yasumasa Komoda, Yuji Hirowatari, Tsuyoshi Akagi et al.
      Pages 140-143
    13. Gotaro Yamada, Motowo Mizuno, Masahiro Takatani, Fumitoshi Kishi, Toshihiko Doi, Rieko Miyamoto et al.
      Pages 144-146
    14. Michiko Shindo, Adrian DiBisceglie, Toshitaka Akatsuka, Tse-Ling Fong, Mikhail Donets, Jay H. Hoofnagle et al.
      Pages 147-149
  6. Immunology and Pathogenesis

    1. Front Matter
      Pages 151-151
    2. Immunopathogenesis

      1. Peter Karayiannis, Sara O’Rourke, Jenny Waters, Richard Watts, Howard C. Thomas
        Pages 155-157
      2. Yaron Ilan, Arnon Nagler, Ruth Adler, Shimon Slavin, Daniel Shouval
        Pages 158-161
      3. Geert Leroux-Roels, Els Van Hecke, Jozef Paradijs, Chantal Molitor, Carine Bastin, Pietro Pala et al.
        Pages 168-172

About these proceedings


A series of international symposia on viral hepatitis and liver disease has been held triannially, and called the "Olympics" of this research field. Our book presents the results of the eighth of these "Olympiads" which for the first time, was held in Asia (May 1993, Tokyo). Due to the rapid progress in research on both basic and clinical aspects of viral hepatitis and liver disease, the state of the art in this field is continually being updated, and our book provides a broad and in-depth survey of current work. The major topics in our book include molecular biology of the five known hepatitis viruses (HAV, HBV, HCV, HDV, and HEV), clinical implications of genetic variants of HBV and HCV, interferon treatment of HCV-related liver disease, and worldwide epidemiology and control of viral hepatitis. New subjects not seen in previous books, such as genotypes of HCV, are also covered. Expanding knowledge about the heterogeneity of the HCV genome has revealed a great variety of genotypes as well as their association with host pathogenesis and their varying responsiveness to interferon therapy. The first promising results of efforts to develop a hepatitis C vaccine are also presented. Finally, compared with its predecessors, our book contains many more papers from Asian countries, where the prevalence of viral hepatitis and liver disease is the highest in the world.


Hepatitis Virus Interferon Therapy Liver Disease Viral Hepatitis interferon

Editors and affiliations

  • K. Nishioka
    • 1
  • H. Suzuki
    • 2
  • S. Mishiro
    • 3
  • T. Oda
    • 4
  1. 1.Japanese Red CrossTokyoJapan
  2. 2.Yamanashi Medical CollegeYamanashiJapan
  3. 3.Institute of ImmunologyTokyoJapan
  4. 4.Japanese Red Cross Medical CenterTokyoJapan

Bibliographic information