Nitric Oxide in the Eye

  • Satoshi Kashii
  • Akinori Akaike
  • Yoshihito Honda

Table of contents

  1. Front Matter
    Pages I-IX
  2. Overview

    1. Front Matter
      Pages 1-1
    2. Thom Mittag
      Pages 3-12
  3. Aqueous Dynamics: Mechanisms of Ocular Hypertension and Glaucoma

    1. Front Matter
      Pages 13-13
    2. Michael Wiederholt, Friederike Stumpff, Natalie Dürschner
      Pages 15-30
  4. Ocular Bloodflow: Ocular Atonomic Neurotransmission

  5. The Uvea: Pathophysiology of Uveitis

    1. Front Matter
      Pages 107-107
    2. Hideki Chuman, Tomomi Chuman
      Pages 109-126
    3. Guey-Shuang Wu, Narsing A. Rao
      Pages 127-131
  6. The Retina

    1. Front Matter
      Pages 133-133
    2. Olivier Goureau, Violaine Faure, Yvonne De Kozak, Francine Behar-Cohen, Pablo Dighiero, Yves Courtois
      Pages 135-142
    3. Stuart A. Lipton, Yun-Beom Choi, Nikolaus J. Sucher, H. S.-Vincent Chen
      Pages 143-152
    4. Satoshi Kashii, Yoshihito Honda, Akinori Akaike
      Pages 153-179
  7. Back Matter
    Pages 181-184

About this book


Nitric oxide (NO) is a simple gas with free radical properties. No one would have imagined a role for such a simple substance in the human body. In 1998, R. E Furchgott, E Murad, and L. J. Ignarro received the Nobel prize for their work on NO. Interestingly, Alfred B. Nobel, who invented dynamite by combining nitro­ glycerin with other substances, took nitroglycerin for his chest pain without realizing that NO mediates its action. Now, in addition to its vasodilating action, NO is known to possess many fundamental functions that include neurotrans­ mission, blood pressure control, blood clotting, and immune responses. These diverse functions, conversely, imply that the simple NO molecule may unite neuroscience, physiology, and immunology and may change our understanding of how cells communicate and defend themselves. In this context, the Inter­ national Symposium, Nitric Oxide and Free Radicals, was organized to address current thinking about the widespread distribution and variety of functions of NO in the eye. The symposium was held in Kyoto, Japan, September 28-29 as a Satellite Symposium of the XII International Congress of Eye Research, 1996. The Symposium was the first international gathering of leading scientists and ophthalmologists meeting to present and discuss their most recent results in a specialized area of research, specifically concerning the eye.


Aqueous Dynamics Hypertension Ocular Circulation Ocular Inflammation circulation endothelium eye glaucoma neural cell death nitric oxide pathophysiology physiology retina uveitis

Editors and affiliations

  • Satoshi Kashii
    • 1
  • Akinori Akaike
    • 2
  • Yoshihito Honda
    • 1
  1. 1.Department of Ophthalmology and Visual Sciences Graduate School of MedicineKyoto UniversitySakyo-ku, KyotoJapan
  2. 2.Department of Pharmacology Graduate School of Pharmaceutical SciencesKyoto UniversitySakyo-ku, KyotoJapan

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Tokyo 2000
  • Publisher Name Springer, Tokyo
  • eBook Packages Springer Book Archive
  • Print ISBN 978-4-431-68017-8
  • Online ISBN 978-4-431-67949-3
  • About this book