Ischemic Blood Flow in the Brain

  • Yasuo Fukuuchi
  • Minoru Tomita
  • Atsuo Koto
Conference proceedings

Part of the Keio University Symposia for Life Science and Medicine book series (KEIO, volume 6)

Table of contents

  1. Front Matter
    Pages I-XX
  2. Honorary Lecture

  3. Endothelium, Mechanosensors, Glycocalyx

  4. Endothelium, BBB Disruption

    1. Front Matter
      Pages 47-47
    2. Gary A. Rosenberg, Diedre Hofinger, Edward Y. Estrada, James A. Wallace
      Pages 57-63
    3. Timur D. Vlasov, Victor I. Amosov, Dmitry E. Korzhevski
      Pages 64-69
    4. U. Ito, T. Kuroiwa, S. Hanyu, Y. Hakamata, S. Ito, I. Nakano et al.
      Pages 76-82
  5. Ischemia and Gene Expression

    1. Front Matter
      Pages 89-89
    2. David W. Busija, Ferenc Domoki, Nishadi Thrikawala, Ferenc Bari
      Pages 91-97
    3. Costantino Iadecola, Shigeru Nogawa, Masao Nagayama, Tomiko Nagayama, Kiyoshi Niwa, Xueren Zhao et al.
      Pages 98-107
    4. Norihiro Suzuki, Yasuo Fukuuchi, Atsuo Koto, Yoko Morita, Toshihiko Shimizu, Masaki Takao et al.
      Pages 128-135
    5. Hiroaki Ooboshi, Setsuro Ibayashi, Donald D. Heistad, Masatoshi Fujishima
      Pages 136-141
  6. Ischemic Signal Transduction, Chemical Mediators

    1. Front Matter
      Pages 149-149
    2. Gregory J. Del Zoppo, Takeo Abumiya, Brian Copeland, Gerhard F. Hamann, Ji Hoe Heo, Naohisa Hosomi et al.
      Pages 151-160
    3. Kortaro Tanaka, Yasuo Fukuuchi, Shigeru Nogawa, Eiichiro Nagata, Daisuke Ito, Shigeaki Suzuki et al.
      Pages 168-177
    4. Péter Sándor, Katalin Komjáti, Wybren De Jong, Benedek Erdös, Zsombor Lacza, Zoltán Benyó et al.
      Pages 178-194
    5. Rudolf Graf, Eiji Kumura, Christian Dohmen, Gerhard Rosner, Wolf-Dieter Heiss
      Pages 195-201
    6. Kotaro Ogihara, Alexander Y. Zubkov, Robert E. Tibbs, Andrew D. Parent, John H. Zhang
      Pages 202-208
  7. Visualization of Ischemic Blood Flow

    1. Front Matter
      Pages 209-209
    2. W.-D. Heiss, R. Graf, T. Fujita, K. Ohta, R. Saito, K. Wienhard
      Pages 211-220
    3. Iwao Kanno, Eku Shimosegawa, Hideaki Fujita, Jun Hatazawa
      Pages 221-225
    4. Masaharu Sakoh, Albert Gjedde, Leif Østergaard
      Pages 226-231
    5. Ulrich Dirnagl, Hellmuth Obrig, Wolfram Von Pannwitz, Matthias Kohl, Christian Kerskens, Claudia Döge et al.
      Pages 232-240
    6. Wolfgang Kuschinsky, Johannes Vogel
      Pages 241-248
  8. Vascular Reactivity in Ischemia

    1. Front Matter
      Pages 263-263
    2. Stephen C. Jones, Alexander Kharlamov, Carol R. Radinsky, Yinsheng Qu, Kirk A. Easley
      Pages 265-281
    3. Istvan Schiszler, Minoru Tomita, Yasuo Fukuuchi, Norio Tanahashi, Kouji Inoue
      Pages 282-288
    4. E. Kozniewska, F. Lisdat, B. Ge, R. Reszka
      Pages 296-303
    5. Joseph C. Lamanna, Ita Kaiserman-Abramof, Kui Xu, Shaun Daugherty, Juan Carlos Chávez, Paola Pichiule
      Pages 319-325
    6. Makoto Suematsu, Mayumi Kajimura, Nobuya Makino, Yuzuru Ishimura
      Pages 326-332
  9. Spreading Depression, Oxidative Stress, Penumbra

    1. Front Matter
      Pages 333-333

About these proceedings


Because stroke is essentially a disease of the vessels and blood flow, the most fundamental aspects of ischemic blood flow in the brain are under investigation by researchers. Their work was the focus of the sixth in the series of Keio University International Symposia for Life Sciences and Medicine, held in Tokyo in 1999. Selected here are 55 papers from the symposium, covering the buffy coat (glycocalyx) of endothelial cells, the blood-brain barrier and permeability, gene expression, vascular reactivity, dysregulation, inflammatory deterioration, cortical spreading depression, edema, microvascular derangement, and pathology, in ten major sections. The book includes the thought-provoking discussions that followed the presentations, thus providing an invaluable source of up-to-date information not only for researchers investigating microcirculation but also for clinicians implementing the most effective treatment for stroke patients.


Glycocalyx Inflammatory process in ischemia Ischemic derangement of cerebral blood flow brain circulation depression disturbed vascular reactivity oxidative stress spreading depression stroke

Editors and affiliations

  • Yasuo Fukuuchi
    • 1
  • Minoru Tomita
    • 1
  • Atsuo Koto
    • 1
  1. 1.Department of Neurology School of MedicineKeio UniversityTokyoJapan

Bibliographic information