Clinical Assessment of the Autonomic Nervous System

  • Satoshi Iwase
  • Junichiro Hayano
  • Satoshi Orimo

Table of contents

  1. Front Matter
    Pages i-viii
  2. Sympathetic Microneurography

    1. Front Matter
      Pages 1-1
    2. Satoshi Iwase, Naoki Nishimura, Yuko Kuwahara, Junichi Sugenoya
      Pages 47-71
    3. Satoshi Iwase, Naoki Nishimura, Tadaaki Mano
      Pages 73-92
    4. Hisayoshi Murai, Shuichi Kaneko, Masayuki Takamura
      Pages 93-105
  3. Heart Rate Variability (HRV)

    1. Front Matter
      Pages 107-107
    2. Junichiro Hayano
      Pages 109-127
    3. Ken Kiyono, Junichiro Hayano, Eiichi Watanabe, Yoshiharu Yamamoto
      Pages 147-161
    4. Eiichi Watanabe, Ken Kiyono, Yoshiharu Yamamoto, Junichiro Hayano
      Pages 163-178
  4. Cardiac MIBG Scintigraphy

About this book


This book describes newly developed methods of assessing the autonomic nervous system. Up-to-date information on microneurographic analysis of human cardiovascular and thermoregulatory function in humans, heart rate variability, and131I-metaiodobenzylguanidine (MIBG) scintigraphy are provided. 
Microneurography, which was originally developed as a technique to analyze the afferent muscle spindle, came to be used to analyze sympathetic nerve activity in the mid-1980s. In the twenty-first century, this technique has become prevalent all over the world especially in investigating the pathophysiology of human cardiovascular function. It is also now used in researching human thermoregulatory function. Heart rate variability is another valuable tool in investigating the current status of human vagal function and in predicting future cardiovascular disease. MIBG is also used to assess cardiac noradrenergic function, especially decreases associated with Parkinson’s disease, Lewy body disease, and multisystem atrophy. Overviews of recent advances in these three important assessments are provided by leading experts.
Clinical Assessment of the Autonomic Nervous System is a useful resource for neurologists and researchers of clinical neurophysiology.


Autonomic nervous system Heart rate variability MIBG scintigraphy Sympathetic nerve Autonomic dysfunction

Editors and affiliations

  • Satoshi Iwase
    • 1
  • Junichiro Hayano
    • 2
  • Satoshi Orimo
    • 3
  1. 1.Department of PhyisiologyAichi Medical UniversityNagakuteJapan
  2. 2.Nagoya City UniversityGraduate School of Medical ScienceNagoyaJapan
  3. 3.Department of NeurologyKanto Central HospitalTokyoJapan

Bibliographic information