IgG4-Related Kidney Disease

  • Takao Saito
  • John H. Stone
  • Hitoshi Nakashima
  • Takako Saeki
  • Mitsuhiro Kawano

Table of contents

  1. Front Matter
    Pages i-xi
  2. General Remarks

    1. Front Matter
      Pages 1-1
    2. Shigeyuki Kawa
      Pages 3-24
    3. Masafumi Moriyama, Seiji Nakamura
      Pages 43-54
    4. Takako Saeki, Mitsuhiro Kawano
      Pages 55-63
    5. Marco Lanzillotta, John H. Stone, Emanuel Della-Torre
      Pages 65-72
  3. Features of IgG4-Related Kidney Disease and Associated Conditions

    1. Front Matter
      Pages 73-73
    2. Takao Saito
      Pages 75-83
    3. Shinichi Nishi, Takako Saeki
      Pages 85-96
    4. Dai Inoue, Yoh Zen, Mitsuhiro Kawano, Osamu Matsui, Toshifumi Gabata
      Pages 97-104
    5. Nobuaki Yamanaka
      Pages 115-123
    6. Mariam Priya Alexander, Lynn D. Cornell
      Pages 125-137
    7. Ichiro Mizushima, Dai Inoue, Mitsuhiro Kawano
      Pages 159-171
    8. Takeshi Uehara, Yasunari Fujinaga, Teruyuki Ogawa, Shigeyuki Kawa
      Pages 173-185
    9. Satoshi Hara, Mitsuhiro Kawano, Ichiro Mizushima, Kenichi Harada, Takuma Takata, Takako Saeki et al.
      Pages 187-191
    10. Mitsuhiro Kawano, Kazunori Yamada
      Pages 193-201
    11. Hitoshi Nakashima
      Pages 203-215
  4. Treatment of IgG4-Related Disease and IgG4-Related Kidney Disease

    1. Front Matter
      Pages 217-217
  5. Differential Diagnosis of IgG4-Related Kidney Disease

    1. Front Matter
      Pages 235-235
    2. Yutaka Yamaguchi, Satoshi Hara, Mitsuhiro Kawano
      Pages 237-250
    3. Mitsuhiro Kawano, Satoshi Hara, Yoshifumi Ubara
      Pages 251-260
    4. Takeshi Zoshima, Mitsuhiro Kawano, Satoshi Hara, Michio Nagata
      Pages 261-269
    5. Shinichi Nishi, Shigeo Hara, Naofumi Imai
      Pages 279-289
  6. Lessons from Cases

    1. Front Matter
      Pages 291-291
    2. Eiko Hasegawa, Akinari Sekine, Jun-ichi Inenaga, Takeshi Fujii, Kenichi Ohashi, Yasuharu Sato et al.
      Pages 293-301
    3. Yoko Wada, Koji Matsuo, Yumi Ito, Naofumi Imai, Masaaki Nakano, Takako Saeki et al.
      Pages 303-311

About this book


This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4-RKD). IgG4-related disease (IgG4-RD), which is characterized by an elevated serum IgG4 level and infiltration of systemic organs by IgG4 positive plasma cells, is a newly recognized systemic disease. Diverse renal manifestations including specific tubulointerstitial nephritis, membranous nephropathy, and tumor-like urological diseases extending to the pelvis and urinary tract in IgG4-RD have been reported and are recently attracting attention as IgG4-RKD. In this book, leading researchers in the field present the latest insights into the broad spectrum of IgG4-RKD characteristics. In addition, they provide a detailed explanation of the pathology of IgG4-RKD including comparisons between the kidney and other affected organs, such as the lacrimal, salivary glands and pancreas in the histopathological section. IgG4-Related Kidney Disease will have a major impact on future immunological and nephrological studies and offers a useful resource not only for nephrologists but also general physicians and investigators in related fields.


IgG4 IgG4-related disease IgG4RKD Membranous glomerulonephritis Tubulointerstitial nephritis

Editors and affiliations

  • Takao Saito
    • 1
  • John H. Stone
    • 2
  • Hitoshi Nakashima
    • 3
  • Takako Saeki
    • 4
  • Mitsuhiro Kawano
    • 5
  1. 1.Faculty of MedicineFukuoka UniversityJapan
  2. 2.Rheumatology Clinic / Yawkey 2Massachusetts General HospitalBostonUSA
  3. 3.Department of Internal MedicineFaculty of Medicine Fukuoka UniversityJapan
  4. 4.Department of Internal MedicineNagaoka Red Cross HospitalNagaokaJapan
  5. 5.Division of RheumatologyKanazawa University HospitalKanazawaJapan

Bibliographic information