Table of contents

  1. Front Matter
    Pages i-ix
  2. Basic Research for Innovative Medicine

    1. Front Matter
      Pages 1-1
    2. Edouard Mullarky, Lewis C. Cantley
      Pages 3-23 Open Access
    3. Sihao Liu, Michael Downes, Ronald M. Evans
      Pages 25-37 Open Access
    4. Thorsten Berger, Mary E. Saunders, Tak W. Mak
      Pages 39-49 Open Access
    5. Shin Maeda, Hayato Nakagawa
      Pages 71-77 Open Access
    6. Miki Nishio, Hiroki Goto, Miki Suzuki, Aya Fujimoto, Koshi Mimori, Akira Suzuki
      Pages 79-94 Open Access
    7. Akira Shibuya, Chigusa Nakahashi-Oda, Satoko Tahara-Hanaoka
      Pages 95-107 Open Access
    8. Wataru Nishie, Hiroshi Shimizu
      Pages 109-117 Open Access
    9. Nagahiro Minato
      Pages 119-128 Open Access
  3. Translational Research for Innovative Medicine

    1. Front Matter
      Pages 129-129
    2. Tadamitsu Kishimoto, Sujin Kang, Toshio Tanaka
      Pages 131-147 Open Access
    3. Yoshihiro Ogawa, Takayoshi Suganami, Michiko Itoh, Miyako Tanaka
      Pages 149-156 Open Access
    4. Ken Ebihara, Kazuwa Nakao
      Pages 165-175 Open Access
    5. Scott L. Friedman
      Pages 187-194 Open Access
    6. Motohiro Nishida, Koichiro Kuwahara, Daisuke Kozai, Reiko Sakaguchi, Yasuo Mori
      Pages 195-218 Open Access

About these proceedings


This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.


Cancer Clinical application Metabolism Stem cell Translational research

Editors and affiliations

  • Kazuwa Nakao
    • 1
  • Nagahiro Minato
    • 2
  • Shinji Uemoto
    • 3
  1. 1.Medical Innovation CenterKyoto University Graduate School of MedicineKyotoJapan
  2. 2.Department of Immunology & Cell BiologyKyoto University Graduate School of MedicineKyotoJapan
  3. 3.Department of SurgeryKyoto University Graduate School of MedicineKyotoJapan

Bibliographic information