Anesthesia and Neurotoxicity

  • Yuji¬†Morimoto

Table of contents

  1. Front Matter
    Pages i-viii
  2. Neurotoxicity of the Anesthetics for Developing Brain

    1. Front Matter
      Pages 1-1
    2. Koichi Yuki, Yasushi Mio, Shoichi Uezono
      Pages 33-48
  3. Postoperative Delirium and Cognitive Dysfunction

    1. Front Matter
      Pages 49-49
    2. Kazuyoshi Ishida, Atsuo Yamashita, Satoshi Yamashita, Mishiya Matsumoto
      Pages 59-94
    3. Tatsuo Horiuchi, Tomonori Takazawa, Shigeru Saito
      Pages 95-103
    4. Shigehito Sawamura
      Pages 105-120
    5. Tomoyuki Miyazaki, Yoshikazu Yamaguchi, Takahisa Goto
      Pages 133-150
    6. Shusuke Sekine, Hiroyuki Uchino
      Pages 151-167

About this book


This book, written by leading Japanese experts in the field, describes the latest findings on the neurotoxicity of anesthetics for the developing brain, postoperative delirium and cognitive dysfunction.

It describes the risk factors for postoperative cognitive dysfunction in elderly surgical patients. Since the number of elderly patients undergoing surgery and anesthesia continues to increase, it is important to improve our understanding of the risks and mechanisms of postoperative delirium and cognitive dysfunction, potential ways to prevent or alleviate them and the public health implications.

Recently, it has been shown that using anesthetics on the developing brain causes apoptotic neurodegeneration and persistent learning/memory deficits later in life. Anesthesiologists need more information on this mechanism in the human brain.

The negative effects of anesthesia and surgery on the nervous system have attracted attention lately; this book provides physicians, researchers, and postdocs with invaluable information on this topic.


Anesthetics Neurodegeneration Neurotoxicity Postoperative Cognitive Dysfunction Postoperative Delirium

Editors and affiliations

  • Yuji¬†Morimoto
    • 1
  1. 1.Graduate School of MedicineHokkaido University Graduate, School of MedicineSapporoJapan

Bibliographic information

  • DOI
  • Copyright Information Springer Japan 2017
  • Publisher Name Springer, Tokyo
  • eBook Packages Medicine
  • Print ISBN 978-4-431-55623-7
  • Online ISBN 978-4-431-55624-4
  • Buy this book on publisher's site