Cortical Development

Neural Diversity and Neocortical Organization

  • Ryoichiro Kageyama
  • Tetsuo Yamamori

Table of contents

  1. Front Matter
    Pages i-viii
  2. Hiromi Shimojo, Yuki Maeda, Toshiyuki Ohtsuka, Ryoichiro Kageyama
    Pages 1-17
  3. Julian Heng, François Guillemot
    Pages 19-41
  4. Goichi Miyoshi, Robert P. Machold, Gord Fishell
    Pages 89-126
  5. Fernanda M. Rodríguez-Tornos, Beatriz Cubelos, Marta Nieto
    Pages 127-151
  6. Peng Gao, Khadeejah T. Sultan, Xin-Jun Zhang, Song-Hai Shi
    Pages 153-180
  7. Masayoshi Mishina, Tomoyuki Yoshida, Misato Yasumura, Takeshi Uemura
    Pages 229-247
  8. Wei-Chao Huang, Christopher Gregg
    Pages 249-261
  9. Yusuke Komatsu, Shigeko Toita, Masanari Ohtsuka, Toru Takahata, Shiro Tochitani, Tetsuo Yamamori
    Pages 263-276
  10. Back Matter
    Pages 277-282

About this book


This book reviews recent progress in cortical development research, focusing on the mechanisms of neural stem cell regulation, neuronal diversity and connectivity formation, and neocortical organization. Development of the cerebral cortex, the center for higher brain functions such as cognition, memory, and decision making, is one of the major targets of current research. The cerebral cortex is divided into many areas, including motor, sensory, and visual cortices, each of which consists of six layers containing a variety of neurons with different activities and connections. As this book explains, such diversity in neuronal types and connections is generated at various levels. First, neural stem cells change their competency over time, giving sequential rise to distinct types of neurons and glial cells: initially deep layer neurons, then superficial layer neurons, and lastly astrocytes. The activities and connections of neurons are further modulated via interactions with other brain regions, such as the thalamocortical circuit, and via input from the environment. This book on cortical development is essential reading for students, postdocs, and neurobiologists.


Cortical development Neural progenitor Neuronal connectivity Neuronal diversity Synapse formation

Editors and affiliations

  • Ryoichiro Kageyama
    • 1
  • Tetsuo Yamamori
    • 2
  1. 1.Institute for Virus ResearchKyoto UniversityKyotoJapan
  2. 2.Division of Brain BiologyNational Institute for Basic BiologyOkazakiJapan

Bibliographic information