Erythropoietins, Erythropoietic Factors, and Erythropoiesis

Molecular, Cellular, Preclinical, and Clinical Biology

  • Steven G. Elliott
  • Mary Ann Foote
  • Graham Molineux
Part of the Milestones in Drug Therapy book series (MDT)

Table of contents

  1. Front Matter
    Pages I-XVIII
  2. Background

    1. Front Matter
      Pages 1-1
    2. Bruce E. Torbett, Jeffrey S. Friedman
      Pages 3-18
    3. David R. Mole, Peter J. Ratcliffe
      Pages 19-40
    4. Graham Molineux, Angus M. Sinclair
      Pages 41-60
    5. Josef T. Prchal, Xylina T. Gregg
      Pages 61-74
  3. Erythropoiesis-stimulating agents

    1. Front Matter
      Pages 75-75
    2. Alice S. Chuck, Adrian Distler, Shane A. Sander, Rohini R. Deshpande, Gregg Nyberg, James E. Seely
      Pages 87-104
    3. Huub Schellekens
      Pages 105-114
    4. Steven G. Elliott
      Pages 115-140
  4. Erythropoietin receptor

    1. Front Matter
      Pages 141-141
    2. Harvey F. Lodish, Saghi Ghaffari, Merav Socolovsky, Wei Tong, Jing Zhang
      Pages 155-174
    3. Stefan N. Constantinescu
      Pages 175-196
  5. Clinical utility

    1. Front Matter
      Pages 197-197
    2. Sameer Doshi, Juan Jose Perez-Ruixo, Graham R. Jang, Andrew T. Chow
      Pages 199-223
    3. Don H. Catlin, Caroline K. Hatton
      Pages 249-278
    4. Tara L. Arvedson, Barbra J. Sasu
      Pages 279-298

About this book

Introduction

This second edition is a one-source guide to current information about red blood cell physiology and the action of native and recombinant human erythropoietic factors. Topics in the fields of erythropoiesis, recombinant protein discovery and production, and treatment of patients with anemia due to renal failure, cancer, or chronic diseases are covered. The newest theories in erythropoiesis (receptors, signaling), manufacturing, new formulations, and clinical research are discussed.

 This book is of interest to researchers and clinical investigators in academia and biotechnology and pharmaceutical companies, to clinical research associates, clinical monitors, and physician investigators.

Keywords

Activation anemia biology biotechnology blood cell cancer cell cell physiology erythropoietin metabolism pharmacokinetics physiology regulation research signal transduction

Editors and affiliations

  • Steven G. Elliott
    • 1
  • Mary Ann Foote
    • 2
  • Graham Molineux
    • 3
  1. 1.Amgen Inc.Thousand OaksUSA
  2. 2.MA Foote AssociatesWestlake VillageUSA
  3. 3.Amgen Inc.Thousand OaksUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-7643-8698-6
  • Copyright Information Birkhäuser Basel 2009
  • Publisher Name Birkhäuser Basel
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-7643-8694-8
  • Online ISBN 978-3-7643-8698-6
  • About this book