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Cell and Animal Models in Aging and Dementia Research

  • S. Hoyer
  • D. Müller
  • K. Plaschke
Conference proceedings

Part of the Journal of Neural Transmission book series (NEURAL SUPPL, volume 44)

Table of contents

  1. Front Matter
    Pages I-VIII
  2. H. Oberpichler-Schwenk, J. Krieglstein
    Pages 1-20
  3. J. P. Blass
    Pages 87-95
  4. C. Struys-Ponsar, A. Florence, A. Gauthier, R. R. Crichton, Ph. van den Bosch de Aguilar
    Pages 111-132
  5. W. E. Müller, S. Stoll, K. Scheuer, A. Meichelböck
    Pages 145-158
  6. G. Benzi, A. Gorini, R. Arnaboldi, B. Ghigini, R. F. Villa
    Pages 159-171
  7. R. Schliebs, T. Feist, S. Roßner, V. Bigl
    Pages 195-208
  8. Ch. Czech, C. Masters, K. Beyreuther
    Pages 219-230
  9. I. P. Chessell, P. T. Francis, M-T. Webster, A. W. Procter, P. R. Heath, R. C. A. Pearson et al.
    Pages 231-243
  10. Back Matter
    Pages 269-N3

About these proceedings

Introduction

Although age has been recognized as a risk factor for late-onset dementia of Alzheimer type, its etiology is unknown as yet. Several age-related metabolic abnormalities may thus become important for the pathogenesis of the late-onset form. Studies at the cellular/molecular level in brain tissue are possible post mortem, but lack information on the beginning of the disorder. In this supplement, different approaches are dealt with how to induce structural and/or metabolic abnormalities in relevant cell cultures, in brain slices and in experimental animals, and how behavioral changes parallel the metabolic variations.

Keywords

Aging Alzheimer's disease Alzheimer´s disease brain calcium dementia drug ethanol forebrain hypoxia metabolism neurodegenerative disorders neurons neuropathology research

Editors and affiliations

  • S. Hoyer
    • 1
  • D. Müller
    • 1
  • K. Plaschke
    • 1
  1. 1.Institute for Pathochemistry and General NeurochemistryUniversity of HeidelbergHeidelbergFederal Republic of Germany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-7091-9350-1
  • Copyright Information Springer-Verlag Vienna 1994
  • Publisher Name Springer, Vienna
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-211-82549-5
  • Online ISBN 978-3-7091-9350-1
  • Series Print ISSN 0303-6995
  • Buy this book on publisher's site