Cerebral Blood Flow in Acute Head Injury

The Regulation of Cerebral Blood Flow and Metabolism During the Acute Phase of Head Injury, and Its Significance for Therapy

  • Georg Emil Cold

Part of the Acta Neurochirurgica book series (NEUROCHIRURGICA, volume 49)

Table of contents

  1. Front Matter
    Pages I-VIII
  2. Georg Emil Cold
    Pages 1-1
  3. Georg Emil Cold
    Pages 21-23
  4. Georg Emil Cold
    Pages 24-26
  5. Georg Emil Cold
    Pages 27-44
  6. Georg Emil Cold
    Pages 44-47
  7. Back Matter
    Pages 48-64

About this book


During the last decade a multitude of studies concerning the dynamic changes in cerebral blood flow (CBF), cerebral metabolic rate of oxygen (CMRO2), and intracranial pressure (ICP) in the acute phase after head injury have been published. These studies have been supplemented with studies of cerebral autoregulation, CO2 reactivity and barbiturate reactivity. Other investigations include studies of cerebrospinal fluid pH, bicarbonate, lactate and pyruvate. In this book experimental and clinical studies of the dynamic changes in CBF, CMRO2, CO2 reactivity and barbiturate reactivity are reviewed. The author's own clinical studies of the dynamic changes in CBF and cerebral metabolism are summarized and discussed, and the therapeutical implication as regards the use of artificial hyperventilation, sedation with barbiturate and mannitol treatment are discussed.


head head injury intracranial pressure

Authors and affiliations

  • Georg Emil Cold
    • 1
  1. 1.Department of NeuroanesthesiologyÅrthus KommunehospitalÅrhusDenmark

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Vienna 1990
  • Publisher Name Springer, Vienna
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-7091-9103-3
  • Online ISBN 978-3-7091-9101-9
  • Series Print ISSN 0065-1419
  • Buy this book on publisher's site