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Advances in Research on Neurodegeneration

Volume 5

  • P. Riederer
  • D. B. Calne
  • R. Horowski
  • Y. Mizuno
  • W. Poewe
  • M. B. H. Youdim

Part of the Journal of Neural Transmission. Supplementa book series (NEURAL SUPPL, volume 50)

Table of contents

  1. Front Matter
    Pages I-VIII
  2. Brain imaging revisited

    1. Front Matter
      Pages 1-1
    2. T. Brücke, S. Asenbaum, W. Pirker, S. Djamshidian, S. Wenger, Ch. Wöber et al.
      Pages 9-24
    3. S. Bissessur, G. Tissingh, E. Ch. Wolters, Ph. Scheltens
      Pages 25-30
    4. G. Tissingh, J. Booij, A. Winogrodzka, E. A. van Royen, E. Ch. Wolters
      Pages 31-37
  3. Endogenous and exogenous neurotoxins

    1. Front Matter
      Pages 53-53
    2. Yelena Glinka, M. Gassen, M. B. H. Youdim
      Pages 55-66
    3. A. Shirvan, I. Ziv, A. Barzilai, R. Djaldeti, R. Zilkh-Falb, T. Michlin et al.
      Pages 67-78
    4. Etienne C. Hirsch, B. Faucheux, P. Damier, A. Mouatt-Prigent, Y. Agid
      Pages 79-88
  4. Programmed cell death, apoptosis, necrosis and in between

    1. Front Matter
      Pages 113-113
    2. M. Weller, J. B. Schulz, U. Wüllner, P. A. Löschmann, T. Klockgether, J. Dichgans
      Pages 115-123
    3. H. Mochizuki, H. Mori, Y. Mizuno
      Pages 125-140
    4. C. Bancher, H. Lassmann, H. Breitschopf, K. A. Jellinger
      Pages 141-152
    5. Muriel O’Byrne, K. Tipton, G. McBean, H. Kollegger
      Pages 153-164
  5. Immunoinflammatory mechanisms, Infestive diseases causing neurological disorders

    1. Front Matter
      Pages 165-165
    2. H.-P. Hartung, P. Rieckmann
      Pages 173-181
    3. H. Lassmann
      Pages 183-190
    4. H. A. Ketzschmar, A. Giese, D. R. Brown, J. Herms, B. Keller, B. Schmidt et al.
      Pages 191-210
  6. Back Matter
    Pages 211-216

About these proceedings

Introduction

Volume 5 of the series "Advances in Research on Neurodegeneration" is concerned with themes which are currently the focus of intensive research, and in which advances in our understanding of the pathological mechanisms un­ derlying neurodegenerative diseases are expected in the near future. The first section contains five reviews devoted to the various neuroimaging technolo­ gies. The discussion is concerned with the question of whether neuroimaging techniques make it possible to follow the process of degeneration as it occurs, and which methods offer the required sensitivity and quantifiability for this purpose. However, the question needs to be examined of whether, given the physical and chemical limitations of these techniques, even under optimal conditions, anatomical resolution can be improved to the extent that neuro­ degenerative diseases can be diagnosed earlier than currently possible and a confident diagnosis made. The possibilities of using neuroimaging techniques to provide information regarding the effects of neuroprotective or neuroregen­ erative therapeutic strategies, and for correlating the results of neuropsycho­ logical research with imaging data are also discussed. The second section is concerned with the significance of endogenous or exogenous neurotoxins as triggers for neurodegenerative processes that may lead to Parkinsonism. Vulnerability factors, which include such factors as nerve ending sensitivity, the synergistic effects of drugs and the various mechanisms underlying different toxins are discussed.

Keywords

brain brain imaging cell inflammation neurodegenerative disorders research

Editors and affiliations

  • P. Riederer
    • 1
  • D. B. Calne
    • 2
  • R. Horowski
    • 3
  • Y. Mizuno
    • 4
  • W. Poewe
    • 5
  • M. B. H. Youdim
    • 6
  1. 1.Department of PsychiatryUniversity of WürzburgGermany
  2. 2.Neurodegenerative Disorders CentreUniversity of British ColumbiaVancouverCanada
  3. 3.Clinical ResearchSchering AGBerlinGermany
  4. 4.Department of NeurologyJuntendo UniversityTokyoJapan
  5. 5.Department of NeurologyUniversity of InnsbruckAustria
  6. 6.Faculty of MedicineInstitute of Pharmacology, Technion — Israel Institute of TechnologyHaifaIsrael

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-7091-6842-4
  • Copyright Information Springer-Verlag Vienna 1997
  • Publisher Name Springer, Vienna
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-211-82898-4
  • Online ISBN 978-3-7091-6842-4
  • Series Print ISSN 0303-6995
  • Buy this book on publisher's site