Progressive Supranuclear Palsy: Diagnosis, Pathology, and Therapy

  • E. Tolosa
  • R. Duvoisin
  • F. F. Cruz-Sánchez
Conference proceedings

Part of the Journal of Neural Transmission. Supplementa book series (NEURAL SUPPL, volume 42)

Table of contents

  1. Front Matter
    Pages I-X
  2. Clinical aspects

    1. Front Matter
      Pages 1-1
    2. John C. Steele
      Pages 3-14
    3. J. C. Rothwell, M. Vidailhet, P. D. Thompson, A. J. Lees, C. D. Marsden
      Pages 43-50
    4. R. C. Duvoisin
      Pages 51-67
  3. Neuroimage analysis, cerebral blood flow and metabolism

    1. Front Matter
      Pages 91-91
    2. M. Savoiardo, F. Girotti, L. Strada, E. Ciceri
      Pages 93-110
    3. G. Arnold, K. Tatsch, W. H. Oertel, Th. Vogl, J. Schwarz, E. Kraft et al.
      Pages 111-118
  4. Morphological aspects

    1. Front Matter
      Pages 135-135
    2. J. Cervós-Navarro, K. Schumacher
      Pages 153-164
    3. M. Verny, C. Duyckaerts, P. Delaère, Y. He, J.-J. Hauw
      Pages 179-188
    4. J. Winikates, J. Jankovic
      Pages 189-201
  5. Biochemical aspects

  6. Epidemiology and treatment

    1. Front Matter
      Pages 261-261
    2. L. I. Golbe
      Pages 263-273
    3. D. G. Cole, J. H. Growdon
      Pages 283-290
  7. Back Matter
    Pages 291-293

About these proceedings


When Steele, Richardson and Olszewski described Progressive Supranuclear Palsy in Archives of Neurology in 1964, it was thought to be a rare disease. Recent pathological studies of large numbers of patients diagnosed as having Parkinson's disease in life have highlighted the fact that at least one in ten of such cases have some other condition. Progressive Supranuclear Palsy is one of the commonest alternative diagnoses. This book is therefore a timely review of present understanding of Progressive Supranuclear Palsy. Much has been learnt about this sporadic illness of middle and late life although its cause remains unknown, and its treatment continues to be difficult. The Editors have selected a team of authors who review the clinical aspects, neuro-imaging find­ ings, neuropathology, neurochemistry, epidemiology, and therapy of Progres­ sive Supranuclear Palsy. All are to congratulated on producing an excellent and detailed picture of contemporary knowledge of the condition. Anyone interested in Progressive Supranuclear Palsy cannot do better than to start by reading this book. It is to be hoped that it will prompt further investigation to establish its cause and cure. C. D. MARSDEN, London Preface Progressive Supranuclear Palsy (PSP) is a neurodegenerative disorder charac­ terized clinically by the appearance of a supranuclear gaze palsy and extra­ pyramidal features which include bradykinesia and axial dystonia. Postural instability and falls and frontal-type behavioural and cognitive disturbances complete the clinical picture of this progressive disorder.


Supranuclear Palsy antigen brain differential diagnosis metabolism neurochemistry neuroimaging neurology neuropathology Parkinson parkinson's disease pathology PET positron emission tomography (PET) progressive supranuclear palsy research

Editors and affiliations

  • E. Tolosa
    • 1
  • R. Duvoisin
    • 2
  • F. F. Cruz-Sánchez
    • 3
  1. 1.Neurology Service, Hospital Clinic, Faculty of MedicineUniversity of BarcelonaSpain
  2. 2.Neurology ServiceRobert Wood Johnson University HospitalNew BrunswickUSA
  3. 3.Neurological Tissue Bank, Faculty of MedicineUniversity of BarcelonaSpain

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag / Wien 1994
  • Publisher Name Springer, Vienna
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-211-82541-9
  • Online ISBN 978-3-7091-6641-3
  • Series Print ISSN 0303-6995
  • Buy this book on publisher's site