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MAO — The Mother of all Amine Oxidases

  • J. P. M. Finberg
  • M. B. H. Youdim
  • P. Riederer
  • K. F. Tipton
Conference proceedings

Part of the Journal of Neural Transmission. Supplement book series (NEURAL SUPPL, volume 52)

Table of contents

  1. Front Matter
    Pages I-XIX
  2. N. G. G. M. Abeling, A. H. van Gennip, A. G. van Cruchten, H. Overmars, H. G. Brunner
    Pages 9-15
  3. D. L. Murphy, K. Sims, G. Eisenhofer, B. D. Greenberg, T. George, F. Berlin et al.
    Pages 29-38
  4. D. L. Murphy, F. Karoum, D. Pickar, R. M. Cohen, S. Lipper, A. M. Mellow et al.
    Pages 39-48
  5. S. Hocherman, G. Levin, N. Giladi, M. B. H. Youdim
    Pages 63-69
  6. Z. Mészáros, D. Borcsiczky, M. Máté, J. Tarcali, K. Tekes, K. Magyar
    Pages 79-85
  7. O. Yu. Abakumova, O. V. Podobed, T. A. Tsvetkova, I. V. Yakusheva, T. A. Moskvitina, L. I. Kondakova et al.
    Pages 87-91
  8. J. Ekblom, H. Garpenstrand, O. Tottmar, J. A. Prince, L. Oreland
    Pages 93-98
  9. K. Magyar, B. Szende, J. Lengyel, J. Tarczali, I. Szatmáry
    Pages 109-123
  10. R. R. Ramsay
    Pages 139-147
  11. J. G. Richards, J. Saura, J. M. Luque, A. M. Cesura, J. Gottowik, P. Malherbe et al.
    Pages 173-187
  12. I. V. Figueiredo, A. Martinez Coscolla, M. D. Cotrim, M. M. Caramona, B. A. Callingham
    Pages 217-223
  13. J. T. Guimarães, M. Q. Paiva, D. Moura, S. Guimarães
    Pages 225-232
  14. M. Strolin Benedetti, G. Sanson, L. Bona, M. Gallina, S. Persiani, K. F. Tipton
    Pages 233-238
  15. J. M. Lizcano, A Fernández de Arriba, K. F. Tipton, M. Unzeta
    Pages 251-257
  16. T. G. Dowling, S. Cambi, F. Buffoni
    Pages 265-270
  17. M. E. Götz, W. Breithaupt, J. Sautter, A. Kupsch, J. Schwarz, W. H. Oertel et al.
    Pages 271-278
  18. J. Sterling, A. Veinberg, D. Lerner, W. Goldenberg, R. Levy, M. Youdim et al.
    Pages 301-305
  19. Th. Müller, W. Kuhn, R. Krüger, H. Przuntek
    Pages 321-328
  20. A. E. Medvedev, V. I. Shvedov, T. M., O. A. Fedotova, E. Saederup, R. F. Squires
    Pages 337-342
  21. J. A. Morón, V. Perez, E. Fernández-Alvarez, J. L. Marco, M. Unzeta
    Pages 343-349
  22. V. F. Pozdnev, A. Z. Kirkel, N. S. Kamyshanskaya, L. N. Axenova, A. E. Medvedev
    Pages 351-355
  23. Back Matter
    Pages 357-363

About these proceedings

Introduction

Monoamine oxidase (MAO) is linked to psychiatric and neurological disorders, because inhibitors of the enzyme are used clinically for treatment of affective disorders and Parkinson’s disease. One of the interesting new aspects of MAO is the occurrence in the human population of deletions of genes coding for one or the other enzyme subtype (A or B). This leads to the possibility of a genetic basis for psychiatric disorders based on MAO. Subjects with deletions of type A or B, and combined deletions, have been described. In the first group of 6 papers in this book, the occurrence and characterization of these phenotypes, as well as the structure of MAO genes, is explored. Advances in the biochemistry of MAO subtypes and their physiological function and localization in brain and periphery is included. Other sections of the book deal with the neuroprotective action of MAO inhibitors and their pharmacology, especially the pharmacology of new MAO-B inhibitors.

Keywords

MAO Monoamine Oxidase Parkinson's Disease affective disorder inhibitor biochemistry brain cell culture enzyme enzymes metabolism mitochondria Oxidation Parkinson Parkinson's disease pathophysiology pharmacology physiology protein receptor

Editors and affiliations

  • J. P. M. Finberg
    • 1
  • M. B. H. Youdim
    • 1
  • P. Riederer
    • 2
  • K. F. Tipton
    • 3
  1. 1.Department of Pharmacology, The Bruce Rappaport Faculty of MedicineTechnion — Israel Institute of TechnologyHaifaIsrael
  2. 2.Clinical Neurochemistry, Department of PsychiatryUniversity of WürzburgFederal Republic of Germany
  3. 3.Biochemistry DepartmentTrinity CollegeDublinIreland

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-7091-6499-0
  • Copyright Information Springer-Verlag/Wien 1998
  • Publisher Name Springer, Vienna
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-211-83037-6
  • Online ISBN 978-3-7091-6499-0
  • Series Print ISSN 0303-6995
  • Buy this book on publisher's site