Book 2015

Tumor Cell Metabolism

Pathways, Regulation and Biology

Editors:

ISBN: 978-3-7091-1823-8 (Print) 978-3-7091-1824-5 (Online)

Table of contents (16 chapters)

  1. Front Matter

    Pages i-viii

  2. On the Roles of Altered Tumor Cell Metabolism in Tumor Biology

    1. Front Matter

      Pages 1-1

    2. No Access

      Chapter

      Pages 3-22

      Metabolic Remodeling in Bioenergetic Disorders and Cancer

    3. No Access

      Chapter

      Pages 23-43

      Tumor Cell Complexity and Metabolic Flexibility in Tumorigenesis and Metastasis

    4. No Access

      Chapter

      Pages 45-63

      Autophagy and Tumor Cell Metabolism

    5. No Access

      Chapter

      Pages 65-98

      Tumour Hypoxia and the Hypoxia-Inducible Transcription Factors: Key Players in Cancer Progression and Metastasis

  3. Some Specific Regulators of Cellular Metabolism in Normal and Cancer Cells

    1. Front Matter

      Pages 99-99

    2. No Access

      Chapter

      Pages 101-122

      MYC Regulation of Metabolism and Cancer

    3. No Access

      Chapter

      Pages 123-142

      Pyruvate Kinase M2: A Metabolic Tuner

    4. No Access

      Chapter

      Pages 143-163

      Role of the Pentose Phosphate Pathway in Tumour Metabolism

    5. No Access

      Chapter

      Pages 165-171

      Enzymes of the Tumour Metabolome in Diagnostic Applications

    6. No Access

      Chapter

      Pages 173-196

      Contribution of pH Alterations to the Tumor Microenvironment

  4. On the Role of Mitochondria in Tumor Metabolism

    1. Front Matter

      Pages 197-197

    2. No Access

      Chapter

      Pages 199-231

      Mitochondrial Mutations in Cancer Progression: Causative, Bystanders, or Modifiers of Tumorigenesis?

    3. No Access

      Chapter

      Pages 233-256

      The Relevance of the Mitochondrial H+-ATP Synthase in Cancer Biology

    4. No Access

      Chapter

      Pages 257-286

      Canceromics Studies Unravel Tumor’s Glutamine Addiction After Metabolic Reprogramming

    5. No Access

      Chapter

      Pages 287-311

      Essential Role of Mitochondria in Pyrimidine Metabolism

  5. On the New Omics of Metabolism

    1. Front Matter

      Pages 313-313

    2. No Access

      Chapter

      Pages 315-348

      Metabolic Fluxes in Cancer Metabolism

    3. No Access

      Chapter

      Pages 349-372

      Targeted 13C-Labeled Tracer Fate Associations for Drug Efficacy Testing in Cancer

  6. No Access

    Chapter

    Pages E1-E2

    Erratum to Chapter 2: Tumor Cell Complexity and Metabolic Flexibility in Tumorigenesis and Metastasis