Novel Technologies for Vaccine Development

  • Igor S Lukashevich
  • Haval Shirwan

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Preventive Viral-Vectored Vaccines

    1. Front Matter
      Pages 1-1
    2. Chad E. Mire, Thomas W. Geisbert
      Pages 33-60
    3. Evgeniy A. Tkachenko, Tamara K. Dzagurova, Peter E. Tkachenko
      Pages 113-151
    4. Peter Pushko, Peter P. Bredenbeek, Igor S. Lukashevich
      Pages 153-177
  3. Viral-Vectored Therapeutic Cancer Vaccines

    1. Front Matter
      Pages 201-201
    2. Anton V. Borovjagin, Jorge G. Gomez-Gutierrez, Haval Shirwan, Qiana L. Matthews
      Pages 203-271
    3. Kevin J. Harrington
      Pages 273-290
    4. Caroline Jochems, Jeffrey Schlom, James L. Gulley
      Pages 291-327
    5. Tasha Hughes, Howard L. Kaufman
      Pages 329-345
    6. Rajesh K. Sharma, Abhishek K. Srivastava, Hong Zhao, Esma S. Yolcu, Haval Shirwan
      Pages 347-386

About this book


This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a “must read” for all those involved in vaccine development, both in academia and industrial vaccine development.


infectious disease preventive vaccine therapeutic cancer vaccines viral vector vaccine

Editors and affiliations

  • Igor S Lukashevich
    • 1
  • Haval Shirwan
    • 2
  1. 1.Department of Pharmacology and Toxicolog Department of Microbiology and ImmunologUniversity of LouisvilleLouisvilleUSA
  2. 2.Department of Microbiology and ImmunologUniversity of LouisvilleLouisvilleUSA

Bibliographic information