Angiogenesis and Vascularisation

Cellular and Molecular Mechanisms in Health and Diseases

  • Józef Dulak
  • Alicja Józkowicz
  • Agnieszka Łoboda

Table of contents

  1. Front Matter
    Pages i-x
  2. Cells and Mediators

    1. Front Matter
      Pages 1-1
    2. Anna Grochot-Przęczek, Magdalena Kozakowska, Józef Dulak, Alicja Józkowicz
      Pages 3-26
    3. Angelika Chachaj, Andrzej Szuba
      Pages 27-65
    4. Hisamichi Naito, Nobuyuki Takakura
      Pages 67-84
    5. Ester M. Weijers, Victor W. M. van Hinsbergh
      Pages 85-99
    6. Czeslaw S. Cierniewski, Joanna Boncela
      Pages 101-118
  3. Molecular Mechanisms

    1. Front Matter
      Pages 119-119
    2. Leonel Prado-Lourenço, Ahmad M. N. Alhendi, Levon M. Khachigian
      Pages 145-162
    3. Agnieszka Łoboda, Alicja Józkowicz, Józef Dulak
      Pages 163-185
    4. Chandan K. Sen, Yuk Cheung Cyrus Chan
      Pages 187-212
    5. Urszula Florczyk, Alicja Józkowicz, Józef Dulak
      Pages 213-239
    6. Hilda Tsang, Lucio Iannone, Beata Wojciak-Stothard
      Pages 241-260
  4. Diseases and Therapy

    1. Front Matter
      Pages 269-269
    2. Lasse D. Jensen, Pegah Rouhi, Yihai Cao
      Pages 271-291
    3. Dafne Gays, Vera Mugoni, Massimo M. Santoro
      Pages 293-312
    4. Louise L. Dunn, Kim Hoe Chan, Martin K. C. Ng, Roland Stocker
      Pages 313-337
    5. Sofia Konisti, Serafim Kiriakidis, Ewa M. Paleolog
      Pages 339-365
    6. Magdalena Tertil, Klaudia Skrzypek, Agnieszka Łoboda
      Pages 367-387
    7. Maria Paprocka, Catherine Grillon, Danuta Duś, Claudine Kieda
      Pages 389-406
  5. Back Matter
    Pages 407-416

About this book


The book presents  the overview of the current knowledge in some fields of vascular biology, addressing cellular and molecular aspects of blood-vessel formation and their role in health and disease. The major factors involved in the formation of blood vessels are presented by scientists actively involved in this area of research. Special emphasis is put on the presentation of various molecular mechanisms not addressed in similar works to date. The book is divided into three parts. The first part describes the cells and mediators in angiogenesis.  The significance of various populations of potential endothelial progenitors is particularly highlighted. The chapters of the second part focus on molecular mechanisms, with special emphasis on the role of hypoxia, gasotransmitters and reactive oxygen species as well as microRNAs in regulation of angiogenic processes. In the third part, the pathological aspects of disturbed – aggravated or impaired – vascularization are discussed and new modalities for potential therapies are presented.

The book is intended for scientists and PhD students in the fields of vascular biology and cancer research. It may be of interest for medical professionals in the fields of cardiovascular disease, diabetes, oncology and rheumatoid arthritis.


endothelial cells gasotransmitters microRNA oxydative stress reactive oxgen species vessel formation

Editors and affiliations

  • Józef Dulak
    • 1
  • Alicja Józkowicz
    • 2
  • Agnieszka Łoboda
    • 3
  1. 1.Department of Medical BiotechnologyJagiellonian University, Kraków, PolandKrakówPoland
  2. 2.Department of Medical BiotechnologyJagiellonian University, Krakow, PolandKrakowPoland
  3. 3.Department of Medical BiotechnologyJagiellonian UniversityKrakówPoland

Bibliographic information