Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures

  • Jaroslav Sebestik
  • Milan Reinis
  • Jan Jezek

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
    Pages 1-5
  3. Chemistry and Structure of Dendrimers

    1. Front Matter
      Pages 7-7
    2. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 9-22
    3. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 23-27
    4. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 29-44
    5. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 45-54
    6. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 55-81
    7. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 83-92
    8. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 93-98
    9. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 99-102
  4. Dendrimers and Their Biological and Therapeutic Applications

    1. Front Matter
      Pages 103-103
    2. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 105-109
    3. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 111-114
    4. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 115-129
    5. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 131-140
    6. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 141-147
    7. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 149-159
    8. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 161-170
    9. Jaroslav Šebestík, Milan Reiniš, Jan Ježek
      Pages 171-173

About this book

Introduction

Dendrimers are repeatedly branched and roughly spherical large molecules. They can be used in various medical applications, such as anticancer polymeric nanomedicines and nanocarriers, gene carriers and vectors in gene delivery, contrast agents for molecular imaging and vaccines against infectious diseases and cancer. The highly branched, multivalent nature and molecular architecture of dendrimers make them ideal tools for a variety of tissue engineering applications. This book describes different categories of dendrimers, their biomedical and physico-chemical applications as well as convergent and divergent syntheses, click chemistry and ligation strategies. It is a rich source of information for researchers in biochemistry and pharmacology working on drug development as well as for organic chemists who are engaged in synthesis of dendrimers.

Keywords

dendrimers glycopeptide dendrimers nanomedicine

Authors and affiliations

  • Jaroslav Sebestik
    • 1
  • Milan Reinis
    • 2
  • Jan Jezek
    • 3
  1. 1.AS CR, Department of Molecular SpectroscopyInst. of Organic Chemistry, BiochemistryPragueCzech Republic
  2. 2.Institute of Molecular Genetics AS CRPragueCzech Republic
  3. 3., Laboratory of GlycoconjugatesInst. of Organic Chemistry, BiochemistryPragueCzech Republic

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-7091-1206-9
  • Copyright Information Springer-Verlag Wien 2012
  • Publisher Name Springer, Vienna
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-7091-1205-2
  • Online ISBN 978-3-7091-1206-9
  • About this book