Clinical Pharmacology: Current Topics and Case Studies

  • Markus Müller

Table of contents

  1. Front Matter
    Pages I-XXIV
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Markus Müller
      Pages 3-6
    3. Markus Müller
      Pages 7-18
    4. Marcus Müllner, Hans-Georg Eichler
      Pages 19-31
    5. Anna Bucsics
      Pages 33-50
  3. Clinical Trials

    1. Front Matter
      Pages 51-51
    2. Ernst Singer, Christiane Druml
      Pages 53-61
    3. Brigitte Bloechl-Daum, Christiane Druml
      Pages 63-87
    4. Ulla Derhaschnig, Bernd Jilma
      Pages 89-99
    5. Michael Wolzt, Stefan Aschauer
      Pages 101-111
    6. Harald Herkner, Christoph Male
      Pages 113-141
    7. Sreedharan N. Sabarinath, Rajendra Pratap Singh, Hartmut Derendorf
      Pages 143-155
    8. Gerhard Garhöfer, Leopold Schmetterer
      Pages 167-180
    9. Magdalena Pilz, Johannes Pleiner
      Pages 181-190
  4. Tools in Clinical Pharmacology

    1. Front Matter
      Pages 191-191
    2. Martin Bauer, Oliver Langer
      Pages 193-203
    3. Volker Wacheck
      Pages 225-239
    4. Sandra Eder, Volker Wacheck
      Pages 241-260
  5. Topics in Clinical Pharmacology

    1. Front Matter
      Pages 261-261
    2. Martin Brunner
      Pages 263-279
    3. Markus Zeitlinger
      Pages 281-308
    4. Markus Müller
      Pages 335-344
    5. George Wade, Brigitte Bloechl-Daum
      Pages 345-368
    6. Brigitte Bloechl-Daum, Florence Butlen-Ducuing, Jordi Llinares-Garcia
      Pages 369-386
    7. Christoph Male
      Pages 403-418
  6. Back Matter
    Pages 419-430

About this book


Today we witness an eventful time in which the powerful new forces of genomics, information technology and economics are rapidly changing the science and art of medicine. This will require more specialization than ever before. However, there is also an increasing demand for an integrated approach, which is provided by the discipline of Clinical Pharmacology (CP). CP pursues a scientific goal by studying drug action in patients and volunteers, a clinical goal by administering appropriate drug therapy and a regulatory goal by assessing the risk/benefit ratio of drug candidates in drug development and reimbursement. This introduction to current topics of CP covers traditional topics of clinical drug research and trial methodology but also provides insight in current topics like genomics, imaging technology and issues in drug reimbursement. A number of concrete case studies in clinical drug research and development help to give a better understanding of the general principles of CP.


Alzheimer clinical research clinical trial drug drug development drug research ethics gene therapy kinetics pharmacodynamics pharmacokinetics pharmacology research siRNA vaccine

Editors and affiliations

  • Markus Müller
    • 1
  1. 1.Department of Clinical PharmacologyMedical University Vienna, Vienna General Hospital (AKH)ViennaAustria

Bibliographic information